Title:
MICROBIAL CONSORTIUM AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/152137
Kind Code:
A3
Abstract:
Provided herein are, inter alia, microbial compositions and methods of using the same. The microbial compositions provided include, inter alia, therapeutically effective amounts of Lactobacillus johnsonii, Faecalibacterium prausnitzii, Akkermansia muciniphila, Myxococcus
xanthus and Pediococcus pentosaceus and are particularly useful for methods of treating and preventing inflammatory diseases.
Inventors:
LYNCH SUSAN V (US)
KIMES NIKOLE (US)
VALLADARES RICARDO (US)
LIN DIN L (US)
FUJIMURA KEI (US)
KIMES NIKOLE (US)
VALLADARES RICARDO (US)
LIN DIN L (US)
FUJIMURA KEI (US)
Application Number:
PCT/US2017/020809
Publication Date:
October 05, 2017
Filing Date:
March 03, 2017
Export Citation:
Assignee:
UNIV CALIFORNIA (US)
International Classes:
A61K35/747; A61K35/742; A61K35/744; C12N1/20; G01N33/68; C12R1/01; C12R1/23; C12R1/24
Domestic Patent References:
| WO2007138011A1 | 2007-12-06 | |||
| WO2011094579A2 | 2011-08-04 | |||
| WO2012039615A2 | 2012-03-29 |
Foreign References:
| US20150246081A1 | 2015-09-03 | |||
| CN102132788B | 2012-11-21 |
Other References:
WEINGARDEN, AR ET AL.: "Microbiota Transplantation Restores Normal Fecal Bile Acid Composition in Recurrent Clostridium difficile Infection", AMERICAN JOURNAL OF PHYSIOLOGY - GASTROINTESTINAL AND LIVER PHYSIOLOGY, vol. 306, no. 4, 15 February 2014 (2014-02-15), pages G310 - G319, XP055425865
JANSEN, SS ET AL.: "Differential Induction of Inflammatory Cytokines by Dendritic Cells Treated with Novel TLR-agonist and Cytokine Based Cocktails: Targeting Dendritic Cells in Autoimmunity", JOURNAL OF INFLAMMATION, vol. 7, no. 37, 27 July 2010 (2010-07-27), XP021078249
SOKOL, H ET AL.: "Faecalibacterium prausnitzii is an Anti-inflammatory Commensal Bacterium Identified by Gut Microbiota Analysis of Crohn Disease Patients", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE U.S.A., vol. 105, no. 43, 28 October 2008 (2008-10-28), pages 16731 - 16736, XP002579466
JANSEN, SS ET AL.: "Differential Induction of Inflammatory Cytokines by Dendritic Cells Treated with Novel TLR-agonist and Cytokine Based Cocktails: Targeting Dendritic Cells in Autoimmunity", JOURNAL OF INFLAMMATION, vol. 7, no. 37, 27 July 2010 (2010-07-27), XP021078249
SOKOL, H ET AL.: "Faecalibacterium prausnitzii is an Anti-inflammatory Commensal Bacterium Identified by Gut Microbiota Analysis of Crohn Disease Patients", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE U.S.A., vol. 105, no. 43, 28 October 2008 (2008-10-28), pages 16731 - 16736, XP002579466
Attorney, Agent or Firm:
BOLCOME, Robert, E., III et al. (US)
Download PDF: