MICROCAPILLARY HYBRIDIZATION CHAMBER - SYNGENTA PARTICIPATIONS AG

Title:

MICROCAPILLARY HYBRIDIZATION CHAMBER

Document Type and Number:

WIPO Patent Application WO2003078045

Kind Code:

A3

Abstract:

The invention provides a microcapillay hybridization chamber made of a narrow bore tubing with probe segments. Each probe segment has oligonucleotide probes covalently attached to the inner wall of the tubing and the oligonucleotide probes within each segment have identical, known sequences. Many oligonucleotide probe segments can be present within a single centimeter of tubing. The invention further provides methods fo using the microcapillary hybridization chambers in hybridization assays.

Inventors:

PASZKOWSKI JERZY (CH)
GUTTMAN ANDRAS (US)
WANG XUN (US)

Application Number:

PCT/US2003/007688

Publication Date:

March 25, 2004

Filing Date:

March 12, 2003

Export Citation:

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Assignee:

SYNGENTA PARTICIPATIONS AG (CH)
PASZKOWSKI JERZY (CH)
GUTTMAN ANDRAS (US)
WANG XUN (US)

International Classes:

B01L3/00; C12Q1/68; G01N33/53; C40B40/06; C40B40/10; C40B40/12; C40B50/14; C40B60/14; (IPC1-7): G01N15/06; C12M1/00; C12N11/16; C12Q1/68

Foreign References:

US6294392B1	2001-09-25
US5763263A	1998-06-09

Other References: