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Title:
MICROCHEMICAL CHIP AND REACTION DEVICE
Document Type and Number:
WIPO Patent Application WO/2015/025424
Kind Code:
A1
Abstract:
Provided is a simple and compact microchemical chip that has a fine flow path reliably formed therein through which a valuable specimen of biological origin or a trace amount of a dilute reagent is made to flow; does not break even when a fluid sample is made to flow through pressurization; makes it possible to feed the fluid sample to a flow path accurately, reliably, and as desired; makes it possible to accurately, simply, and quickly analyze a useful substance such as a biological component of the specimen and cause the useful substance to react; and can be produced with a high yield, in large quantities, and so as to be homogeneous. In a microchemical chip (1), a flow path (26) for making a fluid sample selected from a specimen and a reagent flow through pressurization and react chemically passes through a rubber sheet (20); the rubber sheet is sandwiched between metallic, ceramic, glass, or resin base sheets (10, 30); the front and back surfaces of the rubber sheet are coupled to the base sheets (10, 30) directly or through chemical bonding using a silane coupling agent; and holes (11a, 11b) for introducing the fluid sample into the flow path (26) and holes (12a, 12b, 12c) for discharging the fluid sample that has been made to flow through the flow path are formed in a base sheet (10).

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Inventors:
TAKAGI KAZUHISA (JP)
TAKANO TSUTOMU (JP)
Application Number:
PCT/JP2013/072590
Publication Date:
February 26, 2015
Filing Date:
August 23, 2013
Export Citation:
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Assignee:
ASAHI FR R & D CO LTD (JP)
International Classes:
G01N35/08; B01J19/00; B81B1/00; B81C3/00; G01N37/00
Foreign References:
JP2010014407A2010-01-21
JP2012194015A2012-10-11
JP2009115692A2009-05-28
JP2010082540A2010-04-15
JP2005186033A2005-07-14
JP2006187730A2006-07-20
JP2005111567A2005-04-28
JP2005199394A2005-07-28
JP2011133402A2011-07-07
JP2013188677A2013-09-26
JP2006218611A2006-08-24
Other References:
See also references of EP 3037826A4
Attorney, Agent or Firm:
KOMIYA, Yoshio et al. (JP)
Yoshio Komiya (JP)
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