Title:
MICROEMULSIONS FOR SELECTIVE MOLECULAR SEPARATION
Document Type and Number:
WIPO Patent Application WO2003088948
Kind Code:
A3
Abstract:
The subject invention provides unique materials and methods for selectively removing molecules from a medium. In a preferred embodiment of the subject invention, microemulsions are specifically designed to facilitate effective separation of even closely related chemical entities.
Inventors:
DENNIS DONN M (US)
MOREY TIMOTHY E (US)
PARTCH RICHARD E (US)
SHAH DINESH O (US)
VARSHNEY MANOJ (US)
MOREY TIMOTHY E (US)
PARTCH RICHARD E (US)
SHAH DINESH O (US)
VARSHNEY MANOJ (US)
Application Number:
PCT/US2003/013570
Publication Date:
December 04, 2003
Filing Date:
April 22, 2003
Export Citation:
Assignee:
UNIV FLORIDA (US)
DENNIS DONN M (US)
MOREY TIMOTHY E (US)
PARTCH RICHARD E (US)
SHAH DINESH O (US)
VARSHNEY MANOJ (US)
DENNIS DONN M (US)
MOREY TIMOTHY E (US)
PARTCH RICHARD E (US)
SHAH DINESH O (US)
VARSHNEY MANOJ (US)
International Classes:
A61K9/107; A61K31/445; A61K31/55; B01J20/28; (IPC1-7): A61K9/107; A61K31/445; A61K31/55
Other References:
WATARAI H: "Microemulsions in separation sciences", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 780, no. 1-2, 12 September 1997 (1997-09-12), pages 93 - 102, XP004092095, ISSN: 0021-9673
ALTRIA K D: "Background theory and applications of microemulsion electrokinetic chromatography", JOURNAL OF CHROMATOGRAPHY, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 892, no. 1-2, 15 September 2000 (2000-09-15), pages 171 - 186, XP004212062, ISSN: 0021-9673
ALTRIA K D: "Application of microemulsion electrokinetic chromatography to the analysis of a wide range of pharmaceuticals and excipients", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 844, no. 1-2, 4 June 1999 (1999-06-04), pages 371 - 386, XP004170322, ISSN: 0021-9673
XIAOYUN F ET AL: "Microemulsion electrokinetic chromatographic separation of antipyretic analgesic ingredients", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 735, no. 1, 31 May 1996 (1996-05-31), pages 353 - 356, XP004039029, ISSN: 0021-9673
VOMASTOVA L ET AL: "Microemulsion and micellar electrokinetic chromatography of steroids", JOURNAL OF CHROMATOGRAPHY B: BIOMEDICAL APPLICATIONS, ELSEVIER SCIENCE PUBLISHERS, NL, vol. 681, no. 1, 31 May 1996 (1996-05-31), pages 107 - 113, XP004043997, ISSN: 0378-4347
DEBUSSCHERE L ET AL: "Separation of cardiac glycosides by micellar electrokinetic chromatography and microemulsion electrokinetic chromatography", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 779, no. 1-2, 29 August 1997 (1997-08-29), pages 227 - 233, XP004090643, ISSN: 0021-9673
NISHI H ET AL: "Micellar electrokinetic chromatography Perspectives in drug analysis", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 735, no. 1, 31 May 1996 (1996-05-31), pages 3 - 27, XP004039006, ISSN: 0021-9673
NISHI H: "Pharmaceutical applications of micelles in chromatography and electrophoresis", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 780, no. 1-2, 12 September 1997 (1997-09-12), pages 243 - 264, XP004092106, ISSN: 0021-9673
ALTRIA K D: "Background theory and applications of microemulsion electrokinetic chromatography", JOURNAL OF CHROMATOGRAPHY, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 892, no. 1-2, 15 September 2000 (2000-09-15), pages 171 - 186, XP004212062, ISSN: 0021-9673
ALTRIA K D: "Application of microemulsion electrokinetic chromatography to the analysis of a wide range of pharmaceuticals and excipients", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 844, no. 1-2, 4 June 1999 (1999-06-04), pages 371 - 386, XP004170322, ISSN: 0021-9673
XIAOYUN F ET AL: "Microemulsion electrokinetic chromatographic separation of antipyretic analgesic ingredients", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 735, no. 1, 31 May 1996 (1996-05-31), pages 353 - 356, XP004039029, ISSN: 0021-9673
VOMASTOVA L ET AL: "Microemulsion and micellar electrokinetic chromatography of steroids", JOURNAL OF CHROMATOGRAPHY B: BIOMEDICAL APPLICATIONS, ELSEVIER SCIENCE PUBLISHERS, NL, vol. 681, no. 1, 31 May 1996 (1996-05-31), pages 107 - 113, XP004043997, ISSN: 0378-4347
DEBUSSCHERE L ET AL: "Separation of cardiac glycosides by micellar electrokinetic chromatography and microemulsion electrokinetic chromatography", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 779, no. 1-2, 29 August 1997 (1997-08-29), pages 227 - 233, XP004090643, ISSN: 0021-9673
NISHI H ET AL: "Micellar electrokinetic chromatography Perspectives in drug analysis", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 735, no. 1, 31 May 1996 (1996-05-31), pages 3 - 27, XP004039006, ISSN: 0021-9673
NISHI H: "Pharmaceutical applications of micelles in chromatography and electrophoresis", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 780, no. 1-2, 12 September 1997 (1997-09-12), pages 243 - 264, XP004092106, ISSN: 0021-9673
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