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Title:
MICROENCAPSULATION OF Β-ALANINE
Document Type and Number:
WIPO Patent Application WO/2017/114339
Kind Code:
A1
Abstract:
Microencapsulation of β-alanine uses β-alanine as a core material and a mixture of a wall material and an additive as a release material. The additive comprises: a fatty acid-based saturated or unsaturated fatty acid glyceride containing 12-22 carbon atoms and a phospholipid. The fatty acid glyceride is a mono-fatty acid glyceride or a di-fatty acid glyceride, or a mixture formed by mixing the mono-fatty acid glyceride and the di-fatty acid glyceride at arbitrary proportions. The microencapsulation technique solves problems occurring with the use of β-alanine as a raw material, such as high moisture absorption tendency thereof, unpleasant smell and stinging accompanying administration of the same. The invention selects and combines the wall material and the additive to attain a balance between embedment and release with respect to a microencapsulated β-alanine product, and effectively optimizes release kinetics of the product, thereby enabling a stable release of the product, and realizing effective embedment and uniform release. Therefore, the microencapsulated β-alanine is applicable to the preparation of food, drugs, health-enhancing products and functional food.

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Inventors:
WU WENZHONG (CN)
CHEN JIANBIN (CN)
LI QIAN (CN)
LI XIANGCHENG (CN)
Application Number:
PCT/CN2016/111997
Publication Date:
July 06, 2017
Filing Date:
December 25, 2016
Export Citation:
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Assignee:
INNOBIO LTD (CN)
International Classes:
A61K9/50; A61K31/197; A61P21/00
Foreign References:
CN102908337A2013-02-06
CN101744111A2010-06-23
CN105663081A2016-06-15
CN105434402A2016-03-30
CN104258793A2015-01-07
CN101658244A2010-03-03
Other References:
See also references of EP 3398591A4
Attorney, Agent or Firm:
DALIAN GEZHI INTELLECTUAL PROPERTY AGENT LTD. (CN)
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