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Title:
MICROFLUIDIC CHIP AND PREPARATION METHOD AND TEST METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2019/024182
Kind Code:
A1
Abstract:
A microfluidic chip, and a preparation method and a detection method therefor. The microfluidic chip comprises a microfluidic chip substrate and a microfluidic chip cover covering the microfluidic chip substrate. The microfluidic chip substrate is provided with a reaction cell recessed downwards by a pre-determined depth. A liquid inlet hole and a liquid outlet hole separately communicating with the reaction cell are provided on the periphery of the microfluidic chip substrate. The microfluidic chip is made from a COC resin. The used COC resin has high THz transparency, visible light transparency, high biocompatibility, and is low cost. A surface of the cover is decorated with a GO/Au-NPs nanoparticle complex to capture a target protein, thereby achieving highly sensitive detection. The microfluidic chip substrate and the cover are processed separately and are sealed and packed using a double-sided adhesive or a hot melt adhesive. A square annular spacer can be added between the substrate and the cover to control a distance therebetween, ensuring the invention is affordable and reusable.

Inventors:
SUN, Yiwen (No.3688, Nanhai Road Nanshan Distric, Shenzhen Guangdong 0, 518060, CN)
DU, Pengju (No.3688, Nanhai Road Nanshan Distric, Shenzhen Guangdong 0, 518060, CN)
LU, Xingxing (No.3688, Nanhai Road Nanshan Distric, Shenzhen Guangdong 0, 518060, CN)
XIE, Pengfei (No.3688, Nanhai Road Nanshan Distric, Shenzhen Guangdong 0, 518060, CN)
Application Number:
CN2017/101438
Publication Date:
February 07, 2019
Filing Date:
September 12, 2017
Export Citation:
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Assignee:
SHENZHEN UNIVERSITY (No.3688, Nanhai Road Nanshan Distric, Shenzhen Guangdong 0, 518060, CN)
International Classes:
G01N21/3586; B01L3/00; G01N35/00
Attorney, Agent or Firm:
JOHNSON INTELLECTUAL PROPERTY AGENCY (SHENZHEN) (Room 308-309, Knowledge Service BuildingNo.1, Qilin Road, Nanshan Distric, Shenzhen Guangdong 2, 518052, CN)
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