Title:
MICROFLUIDIC DEVICE CAPABLE OF REMOVING MICROBUBBLES IN CHANNEL BY USING POROUS THIN FILM, SAMPLE INJECTION DEVICE FOR PREVENTING INFLOW OF BUBBLES, AND METHOD FOR BONDING PANEL OF MICROFLUIDIC ELEMENT BY USING MOLD-RELEASING FILM
Document Type and Number:
WIPO Patent Application WO/2019/107763
Kind Code:
A1
Abstract:
The present invention relates to a microfluidic device capable of removing microbubbles in a channel by using a porous thin film, the microfluidic device comprising: an upper panel comprising a microfluidic channel through which a fluid passes; a porous thin film attached to the lower surface of the microfluidic channel so as to remove microbubbles included in the fluid that passes through the microfluidic channel; a lower panel contacting the lower surface of the porous thin film and the upper panel, a passage being provided in the lower panel so as to discharge microbubbles, which pass through the porous thin film, to the outside; and a vacuum-suctioning means for vacuum-suctioning the upper panel and the lower panel such that the microfluidic channel, to which the porous thin film is attached, is attached to the lower panel in a vacuum state. The present invention is advantageous in that, by removing bubbles generated in fluid channels of sensors based on microfluidic technology and devices for separation, measurement, cell culturing, and analysis, the same prevents any interference with the flow of fluid in the channels or prevents the bubbles from occupying the volume that is to be occupied by the fluid, thereby substantially improving the efficiency of specific functions such as analysis, separation, and measurement.
Inventors:
HAN KI-HO (KR)
CHO HYUNG-SEOK (KR)
CHO HYUNG-SEOK (KR)
Application Number:
PCT/KR2018/013096
Publication Date:
June 06, 2019
Filing Date:
October 31, 2018
Export Citation:
Assignee:
INJE UNIV INDUSTRY ACADEMIC (KR)
International Classes:
B01L3/00; B32B38/00; B81C1/00; B81C3/00
Foreign References:
| JP3918040B2 | 2007-05-23 | |||
| US20070125434A1 | 2007-06-07 | |||
| KR20170022483A | 2017-03-02 | |||
| JP2015199187A | 2015-11-12 | |||
| KR20060129301A | 2006-12-15 |
Other References:
DERAMI: "Experimental and computational study of gas bubble removal in a microfluidic system using nanofibrous membranes", MICROSYSTEM TECHNOLO- GIES, vol. 23, no. 7, 18 June 2016 (2016-06-18), pages 2685 - 2698, XP036263703, DOI: doi:10.1007/s00542-016-3020-2
Attorney, Agent or Firm:
WIE, Byoung-Gap (KR)
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