Title:
MICROFLUIDIC DEVICE AND METHOD FOR ISOLATION OF NUCLEIC ACIDS
Document Type and Number:
WIPO Patent Application WO/2016/059619
Kind Code:
A3
Abstract:
The present invention concerns a microfluidic device for mechanically induced trapping of molecular interactions comprising at least a first unit cell and a second unit cell, each unit cell comprising - a membrane chamber comprising a membrane, - a flow channel crossing the membrane chamber and having an inlet and an outlet, and the flow channel crossing the first unit cell being different from the flow channel crossing the second unit cell. Another object of the invention is a method for isolation of specifically bound nucleic acids to target molecules on said microfluidic device followed by its recovery and identification.
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Inventors:
ISAKOVA ALINA (CH)
DEPLANCKE BART (CH)
DEPLANCKE BART (CH)
Application Number:
PCT/IB2015/058032
Publication Date:
June 23, 2016
Filing Date:
October 19, 2015
Export Citation:
Assignee:
ECOLE POLYTECH (CH)
International Classes:
B01L3/00
Domestic Patent References:
| WO2004028955A2 | 2004-04-08 |
Foreign References:
| US20130274113A1 | 2013-10-17 | |||
| US20070248971A1 | 2007-10-25 |
Other References:
JONG WOOK HONG ET AL: "Integrated nanoliter systems", NATURE BIOTECHNOLOGY, vol. 21, no. 10, 1 October 2003 (2003-10-01), pages 1179 - 1183, XP055044773, ISSN: 1087-0156, DOI: 10.1038/nbt871
Attorney, Agent or Firm:
BYRNE, Declan (C.P. 5107, Lausanne, CH)
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