MICROFLUIDIC DEVICES AND METHODS FOR CHEMICAL ASSAYS

WIPO Patent Application WO2002041994

A3

An assay device in which to carry out a fluid-phase chemical assay, comprising means for supporting a test substrate, a sample chamber for receiving a fluid sample and at least one fluid control device for controlling the movement of fluid into and/or out of the sample chamber, wherein the fluid control device comprises a fluid outlet chamber in fluid communication with the sample chamber, and a displaceable flexible diaphragm the displacement of which alters the volume of the outlet chamber so as to allow and/or restrict fluid flow between the outlet and sample chambers. The invention also provides assay apparatus incorporating such a device, an assay station for use as part of such apparatus, a fluid control unit for use as part of the assay device and a method of conducting an assay which may involve the use of such apparatus and devices.

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RYAN PAUL THOMAS (GB)
AUTON KEVIN ANDREW (GB)
SCHUROV SERGEI MIKHAILOVICH (GB)
WIGLEY DAVID JOHN (GB)

PCT/GB2001/005158

October 31, 2002

November 22, 2001

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NEXTGEN SCIENCES LTD (GB)
RYAN PAUL THOMAS (GB)
AUTON KEVIN ANDREW (GB)
SCHUROV SERGEI MIKHAILOVICH (GB)
WIGLEY DAVID JOHN (GB)

B01F11/00; B01F13/00; B01L3/00; F16K7/12; G01F1/7086; G01F1/7088; B01L9/00; (IPC1-7): B01L3/00; B01J19/00; F16K1/00

WO2000043748A1

2000-07-27

US5863502A	1999-01-26
US3982438A	1976-09-28
US6075367A	2000-06-13
US6149787A	2000-11-21

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