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Title:
MICROFLUIDIC SYSTEMS FOR ISOLATING MICROVESICLES
Document Type and Number:
WIPO Patent Application WO/2011/063324
Kind Code:
A3
Abstract:
Methods, apparatuses, and systems for isolating microvesicles in a serum sample include flowing a serum sample that includes microvesicles and other particles that have been shed from a cell surface, through a microchannel formed in a microfluidic device.

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Inventors:
IRIMIA DANIEL (US)
TONER MEHMET (US)
CHEN CHIHCHEN (US)
BREAKFIELD XANDRA O (US)
SKOG JOHAN (US)
Application Number:
PCT/US2010/057599
Publication Date:
September 15, 2011
Filing Date:
November 22, 2010
Export Citation:
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Assignee:
GEN HOSPITAL CORP (US)
IRIMIA DANIEL (US)
TONER MEHMET (US)
CHEN CHIHCHEN (US)
BREAKFIELD XANDRA O (US)
SKOG JOHAN (US)
International Classes:
G01N33/53; C12N15/10; C12Q1/68; C12S3/20
Domestic Patent References:
WO2009100029A12009-08-13
WO2007106598A22007-09-20
WO2009015357A12009-01-29
Foreign References:
US5811250A1998-09-22
Other References:
BEAUDOIN A.R. ET AL.: "Detection and Characterization of Microvesicles in the Acinar Lumen and in Juice of Unstimulated Rat Pancreas.", THE JOURNAL OF HISTO CHEMISTRY AND CYTOCHEMISTRY, vol. 34, no. 8, 1986, pages 1079 - 1084
Attorney, Agent or Firm:
DEAN, PH.D., J.D., Sean M. et al. (P.O. Box 1022Minneapolis, Minnesota, US)
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