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Title:
MICROFLUIDIC VORTEX-ASSISTED ELECTROPORATION SYSTEM AND METHOD
Document Type and Number:
WIPO Patent Application WO/2015/021270
Kind Code:
A3
Abstract:
A system and method include delivering cells of interest to multiple traps via a channel connecting the traps, maintaining a vortex flow in the traps to trap the cells of interest in the traps, providing first molecules of interest to the traps, and providing an electric field across the traps to perform electroporation of the first molecules of interest into the cells of interest in the traps.

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Inventors:
HUR SOOJUNG CLAIRE (US)
YUN HOYOUNG (US)
Application Number:
PCT/US2014/050137
Publication Date:
April 02, 2015
Filing Date:
August 07, 2014
Export Citation:
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Assignee:
HARVARD COLLEGE (US)
International Classes:
C12Q3/00; C12N13/00; F15B21/12; F15C1/16; G06K9/00
Domestic Patent References:
WO2011142813A12011-11-17
Foreign References:
US20130171628A12013-07-04
US20110189650A12011-08-04
US6074605A2000-06-13
Other References:
YUN ET AL.: "Sequential multi-molecule delivery using vortex assisted electroporation.", LAB CHIP, vol. 13, no. ISSUE, 21 July 2013 (2013-07-21), pages 2764 - 2772, XP055314397
Attorney, Agent or Firm:
MADDEN, Robert, B. et al. (Lundberg & Woessner P.A.,P.O. Box 293, Minneapolis MN, US)
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