Title:
MICRONEEDLE DEVICES AND PRODUCTION THEREOF
Document Type and Number:
WIPO Patent Application WO2002064193
Kind Code:
A3
Abstract:
Microneedle devices (10) and methods of manufacture are provided for transport of molecules or energy across or into biological barriers, such as skin. The device can comprise one or more microneedles (12) formed of a first material and a second material, wherein the second material is dispersed throughout the first material or forms a portion of the microneedle. The first material preferably is a polymer. The second material can be pore forming agents, structural components, a biosensor, or molecules for release, such as drug. The device also can comprise a substrate (19) and a plurality of microneedles extending from the substrate, wherein the microneedles have a beveled or tapered tip portion, a longitudinally extending exterior channel, or both. Methods of making these devices include providing a mold having a plurality of microdepressions which define the surface of a microneedle; filling the microdepressions with a first molding material; and molding the material, thereby forming microneedles.
Inventors:
PARK JUNG-HWAN
PRAUSNITZ MARK R
PRAUSNITZ MARK R
Application Number:
PCT/US2001/049018
Publication Date:
January 16, 2003
Filing Date:
December 14, 2001
Export Citation:
Assignee:
GEORGIA TECH RES INST (US)
International Classes:
A61B5/15; A61M37/00; A61N1/30; B81C1/00; (IPC1-7): A61M37/00; A61B17/20; A61N1/30
Domestic Patent References:
| WO1999064580A1 | 1999-12-16 | |||
| WO2000035530A1 | 2000-06-22 | |||
| WO2000074763A2 | 2000-12-14 |
Foreign References:
| US3072122A | 1963-01-08 |
Other References:
PATRIK GRISS: "micromachined Electrodes for Biopotential Measurements", 24 May 2000, JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, FINLAND, XP002209872, 10
See also references of EP 1345646A2
See also references of EP 1345646A2
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