Title:
MICROORGANISM MASS SPECTROMETRY METHOD
Document Type and Number:
WIPO Patent Application WO/2023/282061
Kind Code:
A1
Abstract:
This mass spectrometry method comprises: (11) forming, on a sample plate, a mixed crystal of a matrix material and a microorganism sample, which is a sample including a subject microorganism or a component derived from the subject microorganism; (12) performing, with a mass spectrometry device for performing analysis through matrix assisted laser desorption/ionization mass spectrometry, a first laser irradiation in which a predetermined micro region on the mixed crystal is irradiated for a predetermined number of times; (13) performing, with the mass spectrometry device, a second laser irradiation in which the micro region or a predetermined region in the micro region is irradiated for a predetermined number of times; and (14) generating mass spectrometry data indicating a mass spectrometry result for the mixed crystal, on the basis of ion detection signals acquired by the mass spectrometry device during the second laser irradiation. Accordingly, microorganism-derived ions can be detected with sufficiently high signal intensity.
Inventors:
TERAMOTO KANAE (JP)
Application Number:
PCT/JP2022/024863
Publication Date:
January 12, 2023
Filing Date:
June 22, 2022
Export Citation:
Assignee:
SHIMADZU CORP (JP)
International Classes:
G01N27/62; H01J49/16
Foreign References:
| JP2020087639A | 2020-06-04 | |||
| JP2010205460A | 2010-09-16 | |||
| US20200075304A1 | 2020-03-05 |
Other References:
SHIMADZU CORPORATION, AXIMA MICROORGANISM IDENTIFICATION SYSTEM SIMPLE USER GUIDE, 6 April 2017 (2017-04-06)
Attorney, Agent or Firm:
KYOTO INTERNATIONAL PATENT LAW OFFICE (JP)
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