Title:
MICROORGANISM PRODUCING BIORETINOL AND METHOD FOR PRODUCING BIORETINOL USING SAME
Document Type and Number:
WIPO Patent Application WO/2020/111890
Kind Code:
A1
Abstract:
The present invention relates to a microorganism producing retinol into which a retinol biosynthetic gene is introduced, and a method for producing retinol comprising a step of culturing same. The microorganism of the present invention has improved retinol production capacity, and therefore, can be efficiently used to produce retinol and can improve retinol production efficiency on the basis of the method for producing retinol comprising the step of culturing the microorganism.
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Inventors:
YU BYUNG JO (KR)
JANG IN SEUNG (KR)
JANG JI YEON (KR)
JANG IN SEUNG (KR)
JANG JI YEON (KR)
Application Number:
PCT/KR2019/016783
Publication Date:
June 04, 2020
Filing Date:
November 29, 2019
Export Citation:
Assignee:
KOREA INST IND TECH (KR)
International Classes:
C12N15/81; C12N9/02; C12N9/04; C12N9/10; C12P23/00
Foreign References:
| KR20140147982A | 2014-12-31 | |||
| KR20130014673A | 2013-02-08 |
Other References:
JANG, I.-S. ET AL: "Improving the efficiency of homologous recombination by chemical and biological approaches in Yarrowia lipolytica", PLOS ONE, vol. 13, no. 3, 22 March 2018 (2018-03-22), pages e0194954, XP055713156
CASTELBLANCO-MATIZ, L. M.: "Carotenoid production and gene expression in an astaxanthin-overproducing Xanthophyllomycesdendrorhous mutant strain", ARCHIVES OF MICROBIOLOGY, vol. 197, no. 10, 2015, pages 1129 - 1139, XP035574818
JANG, H.-J. ET AL: "Selective retinol production by modulating the composition of retinoids from metabolically engineered E. coli", BIOTECHNOLOGY AND BIOENGINEERING, August 2015 (2015-08-01), pages 16 04 - 1612, XP055480463
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
F.M. AUSUBEL ET AL.: "Current Protocols in Molecular Biology", JOHN WILEY & SONS
See also references of EP 3907290A4
CASTELBLANCO-MATIZ, L. M.: "Carotenoid production and gene expression in an astaxanthin-overproducing Xanthophyllomycesdendrorhous mutant strain", ARCHIVES OF MICROBIOLOGY, vol. 197, no. 10, 2015, pages 1129 - 1139, XP035574818
JANG, H.-J. ET AL: "Selective retinol production by modulating the composition of retinoids from metabolically engineered E. coli", BIOTECHNOLOGY AND BIOENGINEERING, August 2015 (2015-08-01), pages 16 04 - 1612, XP055480463
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
F.M. AUSUBEL ET AL.: "Current Protocols in Molecular Biology", JOHN WILEY & SONS
See also references of EP 3907290A4
Attorney, Agent or Firm:
SON, Min (KR)
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