MICROORGANISMS FOR BIOSYNTHESIS OF LIMONENE ON GASEOUS SUBSTRATES

Title:

MICROORGANISMS FOR BIOSYNTHESIS OF LIMONENE ON GASEOUS SUBSTRATES

Document Type and Number:

WIPO Patent Application WO/2015/027209

Kind Code:

A3

Abstract:

Engineered microorganisms are provided that convert gaseous substrates, such as producer gas, into limonene. In some embodiments, limonene is pumped out of the cell via an efflux pump. In some embodiments, limonene, produced as described herein, is converted through catalytic dimerization into jet fuel. Producer gas used in the processes described herein for production of limonene may be derived from sources that include gasification of waste feedstock and/or biomass residue, waste gas from industrial processes, or natural gas, biogas, or landfill gas.

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Inventors:

JANNSON CHRISTER (US)
CARR CODY A MARCUS (US)
REED JOHN S (US)

Application Number:

PCT/US2014/052386

Publication Date:

May 21, 2015

Filing Date:

August 22, 2014

Export Citation:

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Assignee:

KIVERDI INC (US)

International Classes:

C12P1/04; C12N1/20; C12N15/00; C12N15/74; C12P5/00; C12P21/06

Domestic Patent References:

WO2007139924A2

2007-12-06

Foreign References:

US20120064622A1	2012-03-15
US20110294183A1	2011-12-01
US20120205284A1	2012-08-16
US20130130345A1	2013-05-23

Other References:

POEHLEIN ET AL.: "Complete Genome Sequence of the Type Strain Cupriavidus necator N-1 J.", BACTERIOL, vol. 193, no. 18, September 2011 (2011-09-01), pages 5017, XP055321185
DATABASE PROTEIN [online] 27 June 2013 (2013-06-27), POEHLEIN,A. ET AL: "multidrug resistance protein MexB [Cupriavidus necator N-1]", XP055335356, accession no. NCBI Database accession no. YP_004685497
DATABASE PROTEIN [online] 27 June 2013 (2013-06-27), POEHLEIN,A. ET AL: "acriflavine resistance protein B [Cupriavidus necator N-1]", XP008183114, accession no. NCBI Database accession no. YP_004687455
DATABASE PROTEIN [online] 27 June 2013 (2013-06-27), POEHLEIN,A. ET AL: "cation/multidrug efflux pump [Cupriavidus necator N-1]", XP008183041, accession no. NCBI Database accession no. YP_004687080

Attorney, Agent or Firm:

JACOBSON, Jill A. (LLP2784 Homestead Rd. #32, Santa Clara California, US)

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