Title:
MICROORGANISMS HAVING CARBON DIOXIDE FIXATION PATHWAY INTRODUCED THEREINTO
Document Type and Number:
WIPO Patent Application WO/2014/115816
Kind Code:
A1
Abstract:
A microorganism having a pathway, said pathway comprising: an enzymatic reaction from glyoxylic acid to glycine; an enzymatic reaction from glycine to serine; and an enzymatic reaction from serine to pyruvic acid or an enzymatic reaction from serine to 3-hydroxypyruvic acid.
A microorganism having a pathway, said pathway comprising: an enzymatic reaction from phosphoenolpyruvic acid and CO2 to oxaloacetic acid or an enzymatic reaction from pyruvic acid and CO2 to oxaloacetic acid; an enzymatic reaction from oxaloacetic acid to malic acid; an enzymatic reaction from malic acid to malyl-CoA; an enzymatic reaction from malyl-CoA to glyoxylic acid and acetyl-CoA; an enzymatic reaction from glyoxylic acid and pyruvic acid to 4-hydroxy-2-oxoglutaric acid; an enzymatic reaction from 4-hydroxy-2-oxoglutaric acid to 4-oxoglutaconic acid; and an enzymatic reaction from 4-oxoglutaconic acid to 2-oxoglutaric acid.
Inventors:
FUJII RYOTA (SG)
MATSUMOTO YOSHIKO (JP)
HIDESAKI TOMONORI (SG)
MATSUMOTO YOSHIKO (JP)
HIDESAKI TOMONORI (SG)
Application Number:
PCT/JP2014/051403
Publication Date:
July 31, 2014
Filing Date:
January 23, 2014
Export Citation:
Assignee:
MITSUI CHEMICALS INC (JP)
International Classes:
C12N1/21; C12P7/04; C12P7/30; C12P13/14; C12P19/32
Domestic Patent References:
| WO2011099006A2 | 2011-08-18 | |||
| WO2009008377A1 | 2009-01-15 | |||
| WO2013018734A1 | 2013-02-07 |
Foreign References:
| JP2009148222A | 2009-07-09 |
Other References:
SYLVIA HERTER ET AL.: "Autotrophic C02 Fixation by Chloroflexus aurantiacus: Study of Glyoxylate Formation and Assimilation via the 3-Hydroxypropionate Cycle", JOURNAL OF BACTERIOLOGY, vol. 183, no. 14, 2001, pages 4305 - 4316
SYLVIA HERTER ET AL.: "A Bicyclic Autotrophic C02 Fixation Pathway in Chloroflexus aurantiacus", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, no. 23, 2002, pages 20277 - 20283
GEORG FUCHS: "CO2 fixation in acetogenic bacteria: Variations on a theme", FEMS MICROBIOLOGY LETTERS, vol. 39, no. 3, 1986, pages 181 - 213, XP023921566, DOI: doi:10.1111/j.1574-6968.1986.tb01859.x
BERG I A: "Ecological Aspects of the Distribution of Different Autotrophic CO2 Fixation Pathways", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 77, no. 6, March 2011 (2011-03-01), pages 1925 - 1936, XP055141691, DOI: doi:10.1128/AEM.02473-10
ABSTRACTS OF THE ANNUAL MEETING OF THE SOCIETY FOR BIOTECHNOLOGY, 2010, Japan , Heisei 22 Nendo, pages 225
ABSTRACTS OF THE ANNUAL MEETING OF THE SOCIETY FOR BIOTECHNOLOGY, 2010, Japan , Heisei 22 Nendo, pages 137, 2P-2107
BIOSCIENCE & INDUSTRY, vol. 66, no. 8, 2008, pages 426 - 432
HANA ŠMEJKALOVÁ ET AL: "Methanol Assimilation in Methylobacterium extorquens AM1: Demonstration of All Enzymes and Their Regulation", PLOS ONE, vol. 5, no. 10, 2010, pages e13001, XP055141693, DOI: doi:10.1371/journal.pone.0013001
TOMOKAZU SHIRAI ET AL: "Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis", MICROBIAL CELL FACTORIES, vol. 6, no. 19, 2007, pages 1 - 11
YOHEI SHINFUKU ET AL: "Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum", MICROBIAL CELL FACTORIES, vol. 8, no. 43, 2009, pages 1 - 15
SUNISA CHATSURACHAI ET AL: "An in silico platform for the design of heterologous pathways in nonnative metabolite production", BMC BIOINFORMATICS, vol. 13, no. 93, 2012
SYLVIA HERTER ET AL.: "A Bicyclic Autotrophic C02 Fixation Pathway in Chloroflexus aurantiacus", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, no. 23, 2002, pages 20277 - 20283
GEORG FUCHS: "CO2 fixation in acetogenic bacteria: Variations on a theme", FEMS MICROBIOLOGY LETTERS, vol. 39, no. 3, 1986, pages 181 - 213, XP023921566, DOI: doi:10.1111/j.1574-6968.1986.tb01859.x
BERG I A: "Ecological Aspects of the Distribution of Different Autotrophic CO2 Fixation Pathways", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 77, no. 6, March 2011 (2011-03-01), pages 1925 - 1936, XP055141691, DOI: doi:10.1128/AEM.02473-10
ABSTRACTS OF THE ANNUAL MEETING OF THE SOCIETY FOR BIOTECHNOLOGY, 2010, Japan , Heisei 22 Nendo, pages 225
ABSTRACTS OF THE ANNUAL MEETING OF THE SOCIETY FOR BIOTECHNOLOGY, 2010, Japan , Heisei 22 Nendo, pages 137, 2P-2107
BIOSCIENCE & INDUSTRY, vol. 66, no. 8, 2008, pages 426 - 432
HANA ŠMEJKALOVÁ ET AL: "Methanol Assimilation in Methylobacterium extorquens AM1: Demonstration of All Enzymes and Their Regulation", PLOS ONE, vol. 5, no. 10, 2010, pages e13001, XP055141693, DOI: doi:10.1371/journal.pone.0013001
TOMOKAZU SHIRAI ET AL: "Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis", MICROBIAL CELL FACTORIES, vol. 6, no. 19, 2007, pages 1 - 11
YOHEI SHINFUKU ET AL: "Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum", MICROBIAL CELL FACTORIES, vol. 8, no. 43, 2009, pages 1 - 15
SUNISA CHATSURACHAI ET AL: "An in silico platform for the design of heterologous pathways in nonnative metabolite production", BMC BIOINFORMATICS, vol. 13, no. 93, 2012
Attorney, Agent or Firm:
NAKAJIMA, Jun et al. (JP)
Nakajima 淳 (JP)
Nakajima 淳 (JP)
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