Title:
MICROORGANISMS AND METHODS FOR PRODUCING 2,4-PENTADIENOATE, BUTADIENE, PROPYLENE, 1,3-BUTANEDIOL AND RELATED ALCOHOLS
Document Type and Number:
WIPO Patent Application WO/2013/028519
Kind Code:
A4
Abstract:
The invention provides non-naturally occurring microbial organisms containing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol, crotyl alcohol or 3-buten-1-ol pathways comprising at least one exogenous nucleic acid encoding a butadiene pathway enzyme expressed in a sufficient amount to produce 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol, crotyl alcohol or 3-buten-1-ol. The invention additionally provides methods of using such microbial organisms to produce 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol, crotyl alcohol or 3-buten-1-ol, by culturing a non- naturally occurring microbial organism containing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol, crotyl alcohol or 3-buten-l-ol pathways as described herein under conditions and for a sufficient period of time to produce 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol, crotyl alcohol or 3-buten-1-ol.
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Inventors:
OSTERHOUT ROBIN E (US)
BURGARD ANTHONY P (US)
BURK MARK J (US)
BURGARD ANTHONY P (US)
BURK MARK J (US)
Application Number:
PCT/US2012/051347
Publication Date:
May 10, 2013
Filing Date:
August 17, 2012
Export Citation:
Assignee:
GENOMATICA INC (US)
OSTERHOUT ROBIN E (US)
BURGARD ANTHONY P (US)
BURK MARK J (US)
OSTERHOUT ROBIN E (US)
BURGARD ANTHONY P (US)
BURK MARK J (US)
International Classes:
C12P7/18
Attorney, Agent or Firm:
GAY, David, A. et al. (222 East 41st StreetNew York, NY, US)
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