Title:
MICROORGANISMS PRODUCING DOCOSAHEXAENOIC ACID AND UTILIZATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/112574
Kind Code:
A1
Abstract:
Provided are: a microorganism belonging to the genus Aurantiochytrium, said microorganism having an 18S rRNA gene having a base sequence represented by any of SEQ ID NOS:1-5; Aurantiochytrium sp. OH4 strain; a microorganism which is a variant obtained using any of the aforesaid microorganisms as a parent strain and has a higher DHA productivity than the parent strain; or Aurantiochytrium sp. LTR23 strain. Also provided are methods for producing a DHA-containing composition, DHA and a DHA alkyl ester via fermentation using these microorganisms.
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Inventors:
UJIHARA TETSURO (JP)
NAGANO MEGUMI (JP)
TABATA KAZUHIKO (JP)
NAGANO MEGUMI (JP)
TABATA KAZUHIKO (JP)
Application Number:
PCT/JP2014/050753
Publication Date:
July 24, 2014
Filing Date:
January 17, 2014
Export Citation:
Assignee:
KYOWA HAKKO BIO CO LTD (JP)
International Classes:
C12N1/12; C12P7/40; C12P7/62; C12N15/09; C12R1/89
Domestic Patent References:
| WO2012077799A1 | 2012-06-14 |
Foreign References:
| JPH09284A | 1997-01-07 | |||
| JPH1072590A | 1998-03-17 | |||
| JPH10310556A | 1998-11-24 | |||
| JP2004501603A | 2004-01-22 | |||
| JPH05503425A | 1993-06-10 | |||
| JPH08502405A | 1996-03-19 | |||
| JPH08509355A | 1996-10-08 | |||
| JPH09284A | 1997-01-07 | |||
| JPH1072590A | 1998-03-17 | |||
| JPH10310556A | 1998-11-24 | |||
| JP2006230403A | 2006-09-07 | |||
| JP2005102680A | 2005-04-21 | |||
| JP2004501603A | 2004-01-22 |
Other References:
YANG, H-L. ET AL.: "Isolation and Characterization of Taiwan ese Heterotrophic Microalgae: Screening of Strains for Docosahexaenoic Acid (DHA) Production", MARINE BIOTECHNOLOGY, vol. 12, April 2010 (2010-04-01), pages 173 - 185, XP019784661
J. PROTOZOAL, vol. 17, 1970, pages 213 - 219
"Single Cell Oils", vol. 6, 2005, AOCS PRESS, pages: 86 - 98
"Single Cell Oils", vol. 8, 2005, AOCS PRESS, pages: 107 - 123
APPL. MICROBIOL. BIOTECHNOL., vol. 49, 1998, pages 72 - 76
BLIGH EG; DYER WJ, CAN. J. BIOCHEM. PHYSIOL., vol. 37, 1959, pages 911
KORETARO TAKAHASHI, JOURNAL OF JAPAN OIL CHEMIST'S SOCIET, vol. 40, 1991, pages 931 - 941
KORETARO TAKAHASHI, JOURNAL OF JAPAN OIL CHEMIST'S SOCIETY, vol. 40, 1991, pages 931 - 941
BLIGH EG; DYER WJ, CAN. J. BIOCHEM. PHYSIOL., 1959, pages 37911
YOKOYAMA R, MYCOSCIENCE, vol. 48, pages 329 - 341
DAISUKE HONDA: "Phylogeny and Taxonomy of the Labyrinthula", KAIYO TO SEIBUTSU (AQUABIOLOGY, vol. 23, 2001, pages 7 - 18
KARLIN; ALTSCHUL, PRO. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5 873, Retrieved from the Internet
See also references of EP 2947141A4
J. PROTOZOAL, vol. 17, 1970, pages 213 - 219
"Single Cell Oils", vol. 6, 2005, AOCS PRESS, pages: 86 - 98
"Single Cell Oils", vol. 8, 2005, AOCS PRESS, pages: 107 - 123
APPL. MICROBIOL. BIOTECHNOL., vol. 49, 1998, pages 72 - 76
BLIGH EG; DYER WJ, CAN. J. BIOCHEM. PHYSIOL., vol. 37, 1959, pages 911
KORETARO TAKAHASHI, JOURNAL OF JAPAN OIL CHEMIST'S SOCIET, vol. 40, 1991, pages 931 - 941
KORETARO TAKAHASHI, JOURNAL OF JAPAN OIL CHEMIST'S SOCIETY, vol. 40, 1991, pages 931 - 941
BLIGH EG; DYER WJ, CAN. J. BIOCHEM. PHYSIOL., 1959, pages 37911
YOKOYAMA R, MYCOSCIENCE, vol. 48, pages 329 - 341
DAISUKE HONDA: "Phylogeny and Taxonomy of the Labyrinthula", KAIYO TO SEIBUTSU (AQUABIOLOGY, vol. 23, 2001, pages 7 - 18
KARLIN; ALTSCHUL, PRO. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5 873, Retrieved from the Internet
See also references of EP 2947141A4
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