Title:
MICTOACTUATOR USING BUNDLED ACTIN FILAMENTS
Document Type and Number:
WIPO Patent Application WO/2006/088214
Kind Code:
A1
Abstract:
A microactuator is fabricated by holding myosin on the surface, loading bundled actin filaments thereon to form a protein construct and three-dimensionally processing the surface so as to allow the bundled actin filaments to serve as an operation member. Thus, an in vitro motility assay system on the baseboard of the bundled actin filaments and a microactuator are provided.
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Inventors:
HINO MIZUKI (JP)
KOHAMA KAZUHIRO (JP)
ISHIKAWA RYOKI (JP)
NAKAMURA AKIO (JP)
SUSAI TAKASHI (JP)
OHATA AKIKO (JP)
OIWA KAZUHIRO (JP)
KOHAMA KAZUHIRO (JP)
ISHIKAWA RYOKI (JP)
NAKAMURA AKIO (JP)
SUSAI TAKASHI (JP)
OHATA AKIKO (JP)
OIWA KAZUHIRO (JP)
Application Number:
PCT/JP2006/303091
Publication Date:
August 24, 2006
Filing Date:
February 15, 2006
Export Citation:
Assignee:
NS TECHNOLOGY INC ADMINISTRATI (JP)
HINO MIZUKI (JP)
KOHAMA KAZUHIRO (JP)
ISHIKAWA RYOKI (JP)
NAKAMURA AKIO (JP)
SUSAI TAKASHI (JP)
OHATA AKIKO (JP)
OIWA KAZUHIRO (JP)
HINO MIZUKI (JP)
KOHAMA KAZUHIRO (JP)
ISHIKAWA RYOKI (JP)
NAKAMURA AKIO (JP)
SUSAI TAKASHI (JP)
OHATA AKIKO (JP)
OIWA KAZUHIRO (JP)
International Classes:
C07K17/14; B81B5/00; B81C1/00; C12N11/14
Foreign References:
| JP2002018799A | 2002-01-22 |
Other References:
OIWA K.: "Protein motors: their mechanical properties and application to nanometer-scale devices", MATERIALS SCIENCE FORUM, vol. 426-432, no. PT. 3, 2003, pages 2339 - 2344, XP002999633
MIHAJLOVIC G. ET AL.: "A reversible switch for actomyosin-based nanoactuators", BIOPHYSICAL JOURNAL, vol. 86, no. 1, January 2004 (2004-01-01), pages 57A 1, XP002999634
PRASSLER J. ET AL.: "Interaction of a Dictyostellium member of the plastin/fimbrin family with actin filaments and actin-myosin complexes", MOLECULAR BIOLOGY OF THE CELL, vol. 8, no. 1, January 1997 (1997-01-01), pages 83 - 95, XP002999635
BING W., FRASER I.D.C., MARSTON S.B.: "Troponin I and troponin T interact with troponin C to produce different Ca2+-dependent effects on actin-tropomyosin filament motility", BIOCHEMICAL JOURNAL, vol. 327, no. 2, 1997, pages 335 - 340, XP002999636
MIHAJLOVIC G. ET AL.: "A reversible switch for actomyosin-based nanoactuators", BIOPHYSICAL JOURNAL, vol. 86, no. 1, January 2004 (2004-01-01), pages 57A 1, XP002999634
PRASSLER J. ET AL.: "Interaction of a Dictyostellium member of the plastin/fimbrin family with actin filaments and actin-myosin complexes", MOLECULAR BIOLOGY OF THE CELL, vol. 8, no. 1, January 1997 (1997-01-01), pages 83 - 95, XP002999635
BING W., FRASER I.D.C., MARSTON S.B.: "Troponin I and troponin T interact with troponin C to produce different Ca2+-dependent effects on actin-tropomyosin filament motility", BIOCHEMICAL JOURNAL, vol. 327, no. 2, 1997, pages 335 - 340, XP002999636
Attorney, Agent or Firm:
Nishizawa, Toshio (11-1 Minami-Aoyama 6-chom, Minato-ku Tokyo, JP)
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