Title:
MID 9002, A HUMAN SULFATASE FAMILY MEMBER AND USES THEREFOR
Document Type and Number:
WIPO Patent Application WO2003020947
Kind Code:
A3
Abstract:
The invention provides isolated nucleic acids molecules, designated MID 9002 nucleic acid molecules, which encode novel sulfatase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MID 9002 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a MID 9002 gene has been introduced or disrupted. The invention still further provides isolated Mill 9002 proteins, fusion proteins, antigenic pep tides and anti-Mill 9002 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
Inventors:
WILLIAMSON MARK (US)
Application Number:
PCT/US2002/026930
Publication Date:
February 05, 2004
Filing Date:
August 23, 2002
Export Citation:
Assignee:
MILLENNIUM PHARM INC (US)
WILLIAMSON MARK (US)
WILLIAMSON MARK (US)
International Classes:
A61K45/00; A61P9/00; A61P35/00; A61P43/00; G01N33/53; C12N9/16; C12N15/09; C12Q1/34; C12Q1/68; C12Q1/6883; G01N33/566; (IPC1-7): C12Q1/68; C12P19/34; C07H21/02; C07H21/04
Other References:
DATABASE GENEBANK [online] February 1998 (1998-02-01), FRANCO B. ET AL.: "Homo sapiens ARSE gene", XP002239376, Database accession no. (X83573)
PUCA A.A. ET AL.: "Identification by shotgun sequencing, genomic organization and functional analysis of a fourth arylsulfatase gene (ARSF) from the Xp22.3 region", GENOMICS, vol. 42, April 1997 (1997-04-01), pages 192 - 199, XP002966658
PUCA A.A. ET AL.: "Identification by shotgun sequencing, genomic organization and functional analysis of a fourth arylsulfatase gene (ARSF) from the Xp22.3 region", GENOMICS, vol. 42, April 1997 (1997-04-01), pages 192 - 199, XP002966658
Download PDF:
Previous Patent: FABRICATION OF MOLECULAR SCALE DEVICES USING FLUIDIC ASSEMBLY
Next Patent: FRET PROTEASE ASSAYS FOR BOTULINUM SEROTYPE A/E TOXINS
Next Patent: FRET PROTEASE ASSAYS FOR BOTULINUM SEROTYPE A/E TOXINS