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Title:
MIGRAINE THERAPEUTIC AGENT
Document Type and Number:
WIPO Patent Application WO/2015/163431
Kind Code:
A1
Abstract:
 Provided is an agent for the prevention/treatment of migraines, the agent containing a compound (1) that exhibits a selective inhibitory action on PDE2A. A compound represented by formula (1): (the symbols in the formula are as described in the specification) or a salt thereof.

Inventors:
IWASHITA HIROKI (JP)
NAKASHIMA MASATO (JP)
ITO YUKI (JP)
Application Number:
PCT/JP2015/062454
Publication Date:
October 29, 2015
Filing Date:
April 23, 2015
Export Citation:
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Assignee:
TAKEDA PHARMACEUTICAL (JP)
International Classes:
A61K31/4985; A61P25/06; A61P43/00
Domestic Patent References:
WO2013161913A12013-10-31
WO2012168817A12012-12-13
Foreign References:
JP2013509442A2013-03-14
JP2004507514A2004-03-11
JP2010506561A2010-03-04
Other References:
MINYAN WANG ET AL.: "Effects of phosphodiesterase inhibition on cortical spreading depression and associated changes in extracellular cyclic GMP", BIOCHEMICAL PHARMACOLOGY, vol. 67, 22 December 2003 (2003-12-22), pages 1619 - 1627, XP055233090
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
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