Title:
MILBEMYCIN OXIME AND PRAZIQUANTEL FLAVOR TABLETS AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/033553
Kind Code:
A1
Abstract:
The present invention relates to a milbemycin oxime and praziquantel flavor tablet and a preparation method therefor. The milbemycin oxime and praziquantel flavor tablet of the present invention consists of a tablet core and a drug-free coating layer coated on the surface of the tablet core. One or more coating layers can be present. The coating layer contains at least one phagostimulant or corrigent. The tablet core consists of a pellet, a glidant, and a lubricant. The preparation process of the milbemycin oxime and praziquantel flavor tablet of the present invention comprises drug-containing powder→micropellet→tablet core→coating layer→flavor tablet. The preparation process is simple, and can uniformly mix a main drug and assistants together, so that the assistants can better function, the stability of the drug is improved, the taste of the drug is improved, and the flavor tablet is suitable for industrial production, and has wide application prospects.
Inventors:
WANG YINGFENG (CN)
XIE DENGLONG (CN)
JI WEI (CN)
CHEN GUOQING (CN)
LUO CHENGJIANG (CN)
WANG YIYUE (CN)
LI YA (CN)
ZHU QIFENG (CN)
XU HONGBO (CN)
ZHANG HUAYING (CN)
LIANG JIN (CN)
ZHANG YAN (CN)
ZHOU YAN (CN)
XIE DENGLONG (CN)
JI WEI (CN)
CHEN GUOQING (CN)
LUO CHENGJIANG (CN)
WANG YIYUE (CN)
LI YA (CN)
ZHU QIFENG (CN)
XU HONGBO (CN)
ZHANG HUAYING (CN)
LIANG JIN (CN)
ZHANG YAN (CN)
ZHOU YAN (CN)
Application Number:
PCT/CN2021/112293
Publication Date:
February 17, 2022
Filing Date:
August 12, 2021
Export Citation:
Assignee:
ZHEJIANG HISUN ANIMAL HEALTHCARE PRODUCTS CO LTD (CN)
International Classes:
A61K9/36; A61K9/22; A61K31/365; A61K31/4985; A61K47/02; A61K47/10; A61K47/20; A61K47/32; A61K47/36; A61K47/38; A61K47/46; A61P33/10; A61P33/14
Foreign References:
| CN112220769A | 2021-01-15 | |||
| CN101933929A | 2011-01-05 | |||
| CN107510669A | 2017-12-26 | |||
| US20030190343A1 | 2003-10-09 | |||
| CN101194672A | 2008-06-11 | |||
| CN105796527A | 2016-07-27 |
Attorney, Agent or Firm:
SINO-CREATIVITY INTELLECTUAL PROPERTY LAW FIRM (CN)
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