MIRNA-CONTAINING COMPOSITION FOR TREATING WOUNDS AND IMPROVING SKIN

WIPO Patent Application WO/2019/103300

A1

The present invention relates to a multi-purpose composition which comprises microRNA (miRNA) as an active ingredient so as to have the effect of wound treatment and skin improvement; particularly, to a composition which comprises, as an active ingredient, miRNA comprising a seed sequence represented by any one of base sequences SEQ ID: 1 to 9; an expression vector comprising same; or a transformant transformed by the expression vector.

JP2003511025	INDUSTRIAL APPLICABILITY Modification of gene expression by ssDNA produced in vivo
JP7114477	Identification, production and use of neoantigens
JP2004504811	DNA encoding the new PROST03 polypeptide

SEO MIN KOO (KR)
YOON SANG WON (KR)
PARK EUN JOO (KR)
LEE WON JONG (KR)
CHOI EUN WOOK (KR)

PCT/KR2018/011320

May 31, 2019

September 21, 2018

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PROSTEMICS CO LTD (KR)

A61K48/00; A23L33/13; A61K8/60; A61K31/7105; A61K31/713; A61Q7/00; A61Q19/00

WO2011029903A1

2011-03-17

US20150232837A1

2015-08-20

DATABASE Nucleotide 4 June 2017 (2017-06-04), "Homo Sapiens microRNA 328 (MIR328), microRNA", XP055617202, retrieved from NCBI Database accession no. 029887.1
NAROZNA. B. ET AL.: "MicroRNA-328 Is Involved in Wound Repair Process in Human Bronchial Epithelial Cells", RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, vol. 242, 25 March 2017 (2017-03-25), pages 59 - 65, XP055618784
CHOI, E. W. ET AL.: "Exosomes from Human Adipose-derived Stem Cells Promote Proliferation and Migration of Skin Fibroblasts", EXPERIMENTAL DERMATOLOGY, vol. 27, 23 September 2017 (2017-09-23), pages 1170 - 1172, XP055618783

LEE, Jae Young (KR)

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