Title:
MIXED FIBRILS
Document Type and Number:
WIPO Patent Application WO2002042321
Kind Code:
A3
Abstract:
Fibrils of two or more different peptides are disclosed; these peptides can be related or unrelated. They have a variety of uses as biomaterials and nanomaterials.
Inventors:
DOBSON CHRISTOPHER MARTIN (GB)
MACPHEE CATHERINE (GB)
MACPHEE CATHERINE (GB)
Application Number:
PCT/GB2001/005190
Publication Date:
December 05, 2002
Filing Date:
November 23, 2001
Export Citation:
Assignee:
ISIS INNOVATION (GB)
DOBSON CHRISTOPHER MARTIN (GB)
MACPHEE CATHERINE (GB)
DOBSON CHRISTOPHER MARTIN (GB)
MACPHEE CATHERINE (GB)
International Classes:
C12M3/00; A61K38/00; A61K38/17; A61K45/00; A61K47/48; A61K49/00; A61P9/00; A61P35/00; A61P35/02; A61P43/00; C07K1/02; C07K7/06; C07K14/47; C07K14/65; C07K17/06; (IPC1-7): C07K14/47
Domestic Patent References:
| WO1997007402A1 | 1997-02-27 | |||
| WO2000017328A2 | 2000-03-30 |
Other References:
MACPHEE, DOBSON: "formation of mixed fibrils demonstrates the generic nature and potential utility of amyloid Nanostructures", J. AM. CHEM. SOC., vol. 122, 27 December 2000 (2000-12-27), pages 12707 - 12713, XP002210029
TAKAHASHI YUTA ET AL: "Mutational analysis of designed peptides that undergo structural transition from alpha helix to beta sheet and amyloid fibril formation.", STRUCTURE (LONDON), vol. 8, no. 9, 2000, pages 915 - 925, XP002210030, ISSN: 0969-2126
See also references of EP 1335937A2
TAKAHASHI YUTA ET AL: "Mutational analysis of designed peptides that undergo structural transition from alpha helix to beta sheet and amyloid fibril formation.", STRUCTURE (LONDON), vol. 8, no. 9, 2000, pages 915 - 925, XP002210030, ISSN: 0969-2126
See also references of EP 1335937A2
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