Title:
MODIFICATION OF PHARMACEUTICAL PREPARATIONS TO MAKE THEM MORE CONDUCIVE TO ULTRASONIC TRANSDERMAL DELIVERY
Document Type and Number:
WIPO Patent Application WO/2016/004443
Kind Code:
A3
Abstract:
A method for improving the ultrasonic transdermal delivery of an drug by modifying the excipient solution to which an active ingredient is intermixed in a drug formulation, whereby the choice of excipient solution is modified to one which will be more conducive to ultrasound and will propagate the drug substance at a higher delivery speed through the skin under ultrasonic excitation An example of such an excipient change includes a conversion from a standard dibasic sodium phosphate containing formulation to one using far less sodium or less preservative compositions. Reduced dibasic sodium phosphate formulation. Responsively to insonification thereof, including: reducing the amount of dibasic sodium phosphate in the formulation to provide a reduced dibasic sodium phosphate formulation; and, making a substance in accordance with the reduced dibasic sodium phosphate formulation.
Inventors:
REDDING BRUCE K (US)
Application Number:
PCT/US2015/039831
Publication Date:
March 24, 2016
Filing Date:
July 09, 2015
Export Citation:
Assignee:
REDDING BRUCE K (US)
International Classes:
A61K9/70
Foreign References:
| US20060188556A1 | 2006-08-24 | |||
| US20060034904A1 | 2006-02-16 |
Attorney, Agent or Firm:
WENGER, Patricia, A. (West Chester, PA, US)
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