Title:
MODIFIED ALGINATES FOR ANTI-FIBROTIC MATERIALS AND APPLICATIONS
Document Type and Number:
WIPO Patent Application WO/2016/019391
Kind Code:
A8
Abstract:
Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body.
Inventors:
VEGAS ARTURO J (US)
DOLOFF JOSHUA C (US)
VEISEH OMID (US)
MA MINGLIN (US)
LANGER ROBERT S (US)
ANDERSON DANIEL G (US)
DOLOFF JOSHUA C (US)
VEISEH OMID (US)
MA MINGLIN (US)
LANGER ROBERT S (US)
ANDERSON DANIEL G (US)
Application Number:
PCT/US2015/043495
Publication Date:
March 02, 2017
Filing Date:
August 03, 2015
Export Citation:
Assignee:
MASSACHUSETTS INST TECHNOLOGY (US)
THE CHILDREN'S MEDICAL CENTER CORP (US)
THE CHILDREN'S MEDICAL CENTER CORP (US)
International Classes:
C08B37/00; A61K47/36; C12N5/00; C12N5/071
Attorney, Agent or Firm:
PABST, Patreas et al. (US)
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