Title:
MODIFIED HOST CELLS AND HYBRID OLIGOSACCHARIDES FOR USE IN BIOCONJUGATE PRODUCTION
Document Type and Number:
WIPO Patent Application WO/2016/020499
Kind Code:
A3
Abstract:
Provided herein are host cells capable of producing hybrid oligosaccharides and polysaccharides, wherein said hybrid oligosaccharides and polysaccharides do not comprise a hexose at the reducing end of their first repeat unit. Also provided herein are hybrid oligosaccharides or polysaccharides and bioconjugates which can be produced by the host cells described herein, wherein said bioconjugates comprise a carrier protein linked to a hybrid oligosaccharide or polysaccharide that does not comprise a hexose at the reducing end of its first repeat unit.
More Like This:
Inventors:
FARIDMOAYER AMIRREZA (CH)
Application Number:
PCT/EP2015/068203
Publication Date:
April 07, 2016
Filing Date:
August 06, 2015
Export Citation:
Assignee:
GLYCOVAXYN AG (CH)
International Classes:
A61K47/48; C07K14/195; C12N1/21; C12N9/10; C12P19/28
Domestic Patent References:
| WO2007125089A2 | 2007-11-08 | |||
| WO2004002495A1 | 2004-01-08 | |||
| WO2005003775A2 | 2005-01-13 | |||
| WO1991018911A2 | 1991-12-12 | |||
| WO2011023764A1 | 2011-03-03 | |||
| WO2014013375A1 | 2014-01-23 | |||
| WO2014095771A1 | 2014-06-26 | |||
| WO2011041003A2 | 2011-04-07 | |||
| WO2011138361A1 | 2011-11-10 | |||
| WO2014072405A1 | 2014-05-15 | |||
| WO2011027116A1 | 2011-03-10 |
Other References:
V. S. TERRA ET AL: "Recent developments in bacterial protein glycan coupling technology and glycoconjugate vaccine design", JOURNAL OF MEDICAL MICROBIOLOGY, vol. 61, no. Pt_7, 19 April 2012 (2012-04-19), pages 919 - 926, XP055107688, ISSN: 0022-2615, DOI: 10.1099/jmm.0.039438-0
Attorney, Agent or Firm:
JOHNSTON, Caroline Louise (Global Patents CN925.1980 Great West Road, Brentford Middlesex TW8 9GS, GB)
Download PDF: