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Title:
MODIFIED POLYMER MEMBRANE MATERIAL HAVING SURFACE COMPOSITE GRAFTED PHOSPHORYLCHOLINE AND HEPARIN ANTICOAGULANT COATING AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2023/046044
Kind Code:
A1
Abstract:
The present application relates to a modified polymer membrane material having a surface composite grafted phosphorylcholine and heparin anticoagulant coating. A preparation method for the modified polymer membrane material comprises the following steps: S1. preparing a polymer membrane material; S2. chemically grafting unsaturated phosphorylcholine and N-(3-aminopropyl)methacrylamide on the surface of the polymer membrane material; S3. cleaning the grafted polymer membrane material obtained in step S2; and S4. grafting heparin on the cleaned grafted polymer membrane material obtained in step S3 by using a carbodiimide chemical method.

Inventors:
HU YANFEI (CN)
LIU HUAN (CN)
HU DIE (CN)
CHEN JINTING (CN)
Application Number:
PCT/CN2022/120718
Publication Date:
March 30, 2023
Filing Date:
September 23, 2022
Export Citation:
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Assignee:
JENSCARE SCIENT CO LTD (CN)
International Classes:
A61L33/06; A61L33/00; C08J5/18; C08J7/12; C08J7/16; C08L75/04
Foreign References:
CN113877006A2022-01-04
CN112316218A2021-02-05
US5344455A1994-09-06
US5229172A1993-07-20
EP0947205A21999-10-06
US20050266038A12005-12-01
Attorney, Agent or Firm:
ADVANCE CHINA IP LAW OFFICE (CN)
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