MODIFIED RELEASE, MULTIPLE UNIT DRUG DELIVERY SYSTEMS

WIPO Patent Application WO2003103637

A3

The invention relates to novel modified release multiple unit systems, and methods of preparing these systems, which can be easily compressed into tablets or filled into capsules or sachets without affecting the desired release characteristics of the pharmaceutical active ingredients incorporated within the systems. The multiple unit tablet includes multiple units. Each unit includes at least one core having an outer surface, a first coating layer surrounding at least a portion of the outer surface of the core and having an outer surface, one or more rate controlling polymers, and one or more one active pharmaceutical ingredients. The coating layer includes one or both of the one or more active pharmaceutical ingredients and the one or more rate controlling polymers. The tablet may further include an outer layer on the outer surface of the unit which includes a material that is one or both of elastic and compressible. The material may be a wax materials, such as polyethylene glycol's (PEGS).

KUMAR PRATIK (IN)
JAIN GIRISH KUMAR (IN)
RAMPAL ASHOK (IN)
NITHIYANANDAM RAVIKUMAR (IN)
RAMAKRISHNAN SANKAR (IN)
RAGHUVANSHI RAJEEV SINGH (IN)

PCT/IB2003/002186

May 13, 2004

June 09, 2003

Click for automatic bibliography generation  

RANBAXY LAB LTD (IN)
KUMAR PRATIK (IN)
JAIN GIRISH KUMAR (IN)
RAMPAL ASHOK (IN)
NITHIYANANDAM RAVIKUMAR (IN)
RAMAKRISHNAN SANKAR (IN)
RAGHUVANSHI RAJEEV SINGH (IN)

A61K9/24; A61K9/26; A61K9/50; A61K9/52; A61K31/00; A61K31/137; A61K31/4965; (IPC1-7): A61K9/24; A61K9/26; A61K9/28; A61K9/52; A61K31/4965; A61K31/137

WO1999012524A1	1999-03-18
WO2003041692A1	2003-05-22

US4713248A	1987-12-15
US5783215A	1998-07-21

View/Download PDF      PDF Help

Previous Patent: ORALLY DISINTEGRATING TABLETS AND PROCESS FOR OBTAINING THEM.

Next Patent: NANOPARTICULATE FORMULATIONS COMPRISING HMG COA REDUCTASE INHIBITOR DERIVATIVES (“STATINS”), NOV...