MOLECULAR AND ATOMIC SCALE EVALUATION OF BIOPOLYMERS

Title:

MOLECULAR AND ATOMIC SCALE EVALUATION OF BIOPOLYMERS

Document Type and Number:

WIPO Patent Application WO2000079257

Kind Code:

A9

Abstract:

A method for evaluating a polymer molecule including linearly connected monomer residues includes providing a polymer molecule in a liquid, contacting the liquid with an insulating solid-state membrane having a detector capable of detecting polymer molecule characteristics, and causing the polymer molecule to traverse a limited region of the solid-state membrane so that monomers of the polymer molecule traverse the limit in sequential order, whereby the polymer molecule interacts linearly with the detector and data suitable to determine polymer molecule characteristics are obtained. The limited region may be defined by a nanometer-sized aperture in the membrane.

Inventors:

BRANTON DANIEL
GOLOVCHENKO JENE
DENISON TIMOTHY J

Application Number:

PCT/US2000/017360

Publication Date:

July 11, 2002

Filing Date:

June 22, 2000

Export Citation:

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Assignee:

HARVARD COLLEGE (US)

International Classes:

B81B1/00; B81C99/00; C12Q1/6869; G01N27/28; G01N27/416; H01L21/66; B01L3/00; (IPC1-7): G01N27/26

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