Title:
MOLECULAR GLUE COMPOUND BASED ON CEREBLON PROTEIN DESIGN AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/051766
Kind Code:
A1
Abstract:
The present disclosure relates to a compound of formula (I) or a salt, an enantiomer, a diastereomer, an isotope-enriched analogue, a solvate, a prodrug or a polymorph thereof, and the use thereof. Further provided in the present disclosure are a pharmaceutical composition comprising the compound of formula (I) or a salt, an enantiomer, a diastereomer, an isotope-enriched analogue, a solvate, a prodrug or a polymorph thereof as an active ingredient, and the use thereof. A series of compounds designed and synthesized in the present disclosure can effectively prevent and/or treat diseases or conditions related to the celeblon protein.
Inventors:
YANG XIAOBAO (CN)
SUN RENHONG (CN)
SUN RENHONG (CN)
Application Number:
PCT/CN2023/117399
Publication Date:
March 14, 2024
Filing Date:
September 07, 2023
Export Citation:
Assignee:
GLUETACS THERAPEUTICS SHANGHAI CO LTD (CN)
International Classes:
C07D401/04; A61K31/454; A61K31/496; A61K31/506; A61K31/517; A61K31/541; A61K31/55; A61K31/675; A61P7/06; A61P35/00; A61P35/02; C07D401/14; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D471/04; C07D471/08; C07D487/08; C07D491/107
Domestic Patent References:
| WO2020118098A1 | 2020-06-11 | |||
| WO2022061348A1 | 2022-03-24 |
Foreign References:
| CN110963994A | 2020-04-07 | |||
| CN105566290A | 2016-05-11 | |||
| CN111285850A | 2020-06-16 | |||
| CN110612294A | 2019-12-24 | |||
| CN111247138A | 2020-06-05 | |||
| CN111606883A | 2020-09-01 | |||
| CN109311900A | 2019-02-05 | |||
| CN113582980A | 2021-11-02 | |||
| CN112321566A | 2021-02-05 | |||
| CN112707900A | 2021-04-27 |
Attorney, Agent or Firm:
SYNCLAW ATTORNEYS (CN)
Download PDF:
Previous Patent: T CELL WITH SILENCED CD59 GENE AND USE THEREOF
Next Patent: ANTENNA STRUCTURE, ANTENNA, AND BASE STATION
Next Patent: ANTENNA STRUCTURE, ANTENNA, AND BASE STATION