Title:
MONO-END-CAPPED AMPHIPATHIC ORGANOSILOXANE MACROMONOMER, SILICONE HYDROGEL, CORNEAL CONTACT LENS AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/141794
Kind Code:
A1
Abstract:
A mono-end-capped amphipathic organosiloxane macromonomer, capable of being well intermixed with different hydrophilic monomers without a solvent and being used for preparing a highly oxygen-permeable and highly hydrophilic silicone hydrogel material. Also provided is a silicone hydrogel, prepared by the mono-end-capped amphipathic organosiloxane macromonomer and the following components by means of polymerization reaction: 5-60 parts of a mono-end-capped amphipathic organosiloxane macromonomer, 0-30 parts of a small molecular silicon monomer, 10-70 parts of a hydrophilic monomer, an initiator, and a cross-linking agent. The silicone hydrogel has a good hydrophilic property, a high light transmission property, and a high oxygen-permeable property. Further provided is a corneal contact lens, made of the silicone hydrogel material, and having the advantages of good oxygen permeability and light transmittance, strong hydrophilicity, and wearing comfort, and the like.
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Inventors:
ZHANG XUEQIN (CN)
WU SHU (CN)
CHEN PING (CN)
HAN XUELIAN (CN)
WANG YUDONG (CN)
WU SHU (CN)
CHEN PING (CN)
HAN XUELIAN (CN)
WANG YUDONG (CN)
Application Number:
PCT/CN2021/079427
Publication Date:
July 07, 2022
Filing Date:
March 06, 2021
Export Citation:
Assignee:
JIANGSU HORIEN CONTACT LENS CO LTD (CN)
UNIV SOUTHEAST (CN)
UNIV SOUTHEAST (CN)
International Classes:
C08F220/28; C08G77/46; C08F222/14; C08F226/02; C08F230/08; C08F290/06; C08J3/075; G02C7/04
Foreign References:
| CN108948282A | 2018-12-07 | |||
| CN104774288A | 2015-07-15 | |||
| CN112831050A | 2021-05-25 | |||
| CN105399954A | 2016-03-16 | |||
| CN105418858A | 2016-03-23 | |||
| CN101503491A | 2009-08-12 | |||
| US20140155515A1 | 2014-06-05 | |||
| US20200291160A1 | 2020-09-17 | |||
| US20130046043A1 | 2013-02-21 | |||
| US20190062485A1 | 2019-02-28 | |||
| US20130300010A1 | 2013-11-14 | |||
| US20170038499A1 | 2017-02-09 |
Other References:
ZHANG XUEQIN, ZHANG RUQING, WU SHU, SUN YING, YANG HONG, LIN BAOPING: "Physically and chemically dual-crosslinked hydrogels with superior mechanical properties and self-healing behavior", NEW JOURNAL OF CHEMISTRY, vol. 44, no. 23, 15 June 2020 (2020-06-15), GB , pages 9903 - 9911, XP055947650, ISSN: 1144-0546, DOI: 10.1039/D0NJ00348D
Attorney, Agent or Firm:
BEIJING FOSTAND INTELLECTUAL PROPERTY AGENCY OFFICE (CN)
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