Title:
MONO-HYDROXY OR DI-HYDROXY DERIVATIVES OF POLYUNSATURATED FATTY ACIDS, PRODUCTION METHOD THEREFOR, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/112310
Kind Code:
A1
Abstract:
The present invention relates to: an enzyme for producing hydroxy derivatives of polyunsaturated fatty acids; a method for producing hydroxy derivatives of polyunsaturated fatty acids by using same; and a complex composition of SPMs, comprising hydroxy derivatives of polyunsaturated fatty acids. The enzyme can produce hydroxy derivatives of polyunsaturated fatty acids through a one-time reaction, thereby being very effectively usable in in-vitro production, and a complex composition of SPMs, comprising hydroxy derivatives of polyunsaturated fatty acids promotes the production of collagen, inhibits the production of NO and the expression of TNF-α and IL-6, and increases the expression of filaggrin and loricrin, thereby being effectively usable in the prevention or reduction of skin aging or wrinkles, the strengthening of skin barriers, or the prevention, alleviation or treatment of skin diseases including atopic dermatitis.
More Like This:
WO/1999/065530 | NrdD |
WO/2008/119082 | ENHANCED PRODUCTION OF FATTY ACID DERIVATIVES |
WO/2018/147799 | PRODUCTION OF FATTY ALCOHOLS IN RHODOSPORIDIUM |
Inventors:
SEO JEONG WOO (KR)
YI JONG JAE (KR)
HEO SUN YEON (KR)
JU JUNG HYUN (KR)
KIM CHUL HO (KR)
OH BAEK ROCK (KR)
LEE GIL YONG (KR)
LEE KYUNG MIN (KR)
CHO HEE WON (KR)
YI JONG JAE (KR)
HEO SUN YEON (KR)
JU JUNG HYUN (KR)
KIM CHUL HO (KR)
OH BAEK ROCK (KR)
LEE GIL YONG (KR)
LEE KYUNG MIN (KR)
CHO HEE WON (KR)
Application Number:
PCT/KR2019/017246
Publication Date:
June 10, 2021
Filing Date:
December 06, 2019
Export Citation:
Assignee:
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
KOLON INC (KR)
KOLON INC (KR)
International Classes:
C12N9/02; A23L33/115; A61K8/365; A61K31/202; A61P17/00; C12P7/64
Foreign References:
KR101971481B1 | 2019-04-23 | |||
KR20180096157A | 2018-08-29 | |||
JP2016537411A | 2016-12-01 | |||
KR20090003281A | 2009-01-09 |
Other References:
DATABASE PROTEIN 19 May 2013 (2013-05-19), ANONYMOUS: "Lipoxygenase [Oscillatoria acuminata)", XP055832074, retrieved from NCBI Database accession no. WP_015148841.1
See also references of EP 4071241A4
See also references of EP 4071241A4
Attorney, Agent or Firm:
CHUNG, Soon-Sung (KR)
Download PDF:
Previous Patent: BUCK CONVERTER
Next Patent: AUTONOMOUS DISTRIBUTION CONTROL SYSTEM FOR EFFICIENTLY INTEGRATEDLY CONTROLLING DIRECT CURRENT BETWE...
Next Patent: AUTONOMOUS DISTRIBUTION CONTROL SYSTEM FOR EFFICIENTLY INTEGRATEDLY CONTROLLING DIRECT CURRENT BETWE...