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Title:
MONOCLONAL ANTIBODIES DIRECTED AGAINST THE G3BP PROTEIN, AND USES
Document Type and Number:
WIPO Patent Application WO1999065947
Kind Code:
A3
Abstract:
The invention concerns monoclonal antibodies directed against the G3BP protein and cell lines producing them. The invention also concerns the use of said antibodies or their derivatives for obtaining medicines and diagnostic reagents.

Inventors:
PARKER FABIENNE (FR)
KENIGSBERG MIREILLE (FR)
DUCHESNE MARC (FR)
BARLAT ISABELLE (FR)
Application Number:
PCT/FR1999/001453
Publication Date:
February 24, 2000
Filing Date:
June 17, 1999
Export Citation:
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Assignee:
AVENTIS PHARMA SA (FR)
PARKER FABIENNE (FR)
KENIGSBERG MIREILLE (FR)
DUCHESNE MARC (FR)
BARLAT ISABELLE (FR)
International Classes:
A61K39/395; A61P35/00; A61P43/00; C07K16/18; C12N5/10; C12N5/20; C12N15/02; C12P21/08; G01N33/574; G01N33/577; A61K38/00; C12R1/91; (IPC1-7): C07K16/18; A61K39/395; C12N5/20; C12N15/06; G01N33/577; G01N33/68
Domestic Patent References:
WO1996016169A11996-05-30
Other References:
F. PARKER ET AL.: "A Ras-GTPase-activating protein SH3-domain-binding protein.", MOLECULAR AND CELLULAR BIOLOGY, vol. 16, no. 6, June 1996 (1996-06-01), Washington, DC, états-unis, pages 2561 - 2569, XP002092186
M. DUCHESNE ET AL.: "Identification of the SH3 domain of GAP as an essential sequence for Ras_GAP-mediated signaling.", SCIENCE, vol. 259, no. 5094, 22 January 1993 (1993-01-22), Washington, DC, états-unis, pages 525 - 528, XP002092187
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