Title:
MONOCLONAL ANTIBODY AGAINST BOTH IL-17A AND IL-17F AND USE OF THE SAME
Document Type and Number:
WIPO Patent Application WO/2018/161340
Kind Code:
A1
Abstract:
Provided is an anti-IL 17 A/F antibody that binds to both IL-17A and IL-17F and inhibits the activities of both IL-17A and IL-17F.The antibody comprises heavy chain CDRs 1-3 represented by SEQ ID NOs:1-3 respectively and light chain CDRs 1-3 represented by SEQ ID NOs:4-6 respectively. The use of the antibody in the manufacture of a medicament for treating diseases associated with IL-17A and/or IL-17F in a subject, and the pharmaceutical composition comprising the antibody are also provided.
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Inventors:
DONG CHEN (CN)
GUO LI (CN)
GUO LI (CN)
Application Number:
PCT/CN2017/076278
Publication Date:
September 13, 2018
Filing Date:
March 10, 2017
Export Citation:
Assignee:
X KANG UNITED BIOPHARMACEUTICAL SCIENCE & TECH CO LTD (CN)
International Classes:
C07K16/24; A61K39/00; A61P37/00
Domestic Patent References:
| WO2009130459A2 | 2009-10-29 | |||
| WO2007106769A2 | 2007-09-20 |
Foreign References:
| CN101563098A | 2009-10-21 | |||
| CN104884473A | 2015-09-02 | |||
| CN102458437A | 2012-05-16 | |||
| CN102083858A | 2011-06-01 | |||
| CN102448493A | 2012-05-09 |
Other References:
WANG, TING ET AL.: "Clinical research of anti-interleukin-17 antibody in the treatment of autoimmune diseases", CHINESE JOURNAL OF NEW DRUGS, vol. 25, no. 22, 29 November 2016 (2016-11-29), pages 2531 - 2536, XP009516730, ISSN: 1003-3734
See also references of EP 3592771A4
See also references of EP 3592771A4
Attorney, Agent or Firm:
CHINA SCIENCE PATENT & TRADEMARK AGENT LTD. (CN)
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