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Title:
MONOCLONAL ANTIBODY AGAINST MELK AND UTILIZATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/043311
Kind Code:
A1
Abstract:
The present invention relates to a monoclonal antibody against MELK. Further, the present invention provides a method for diagnosing a MELK-related disease, a method for detecting a MELK protein, a method for evaluating a drug effect after a treatment with a MELK inhibitor and a method for screening a subject for whom a treatment with a MELK inhibitor is highly efficacious, each method comprising using the aforesaid antibody, and a diagnostic reagent containing the aforesaid antibody.

Inventors:
HARADA, Yosuke (INC. 2-1, Sakado 3-chome, Takatsu-ku, Kawasaki-sh, Kanagawa 12, 〒2130012, JP)
CHUNG, Suyoun (INC. 2-1, Sakado 3-chome, Takatsu-ku, Kawasaki-sh, Kanagawa 12, 〒2130012, JP)
NAKAMURA, Yusuke (INC. 2-1, Sakado 3-chome, Takatsu-ku, Kawasaki-sh, Kanagawa 12, 〒2130012, JP)
Application Number:
JP2017/030443
Publication Date:
March 08, 2018
Filing Date:
August 25, 2017
Export Citation:
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Assignee:
ONCOTHERAPY SCIENCE, INC. (2-1 Sakado 3-chome, Takatsu-ku Kawasaki-sh, Kanagawa 12, 〒2130012, JP)
International Classes:
C12N15/09; C07K16/18; C12P21/02; C12Q1/02; G01N33/15; G01N33/50; G01N33/573; G01N33/574
Attorney, Agent or Firm:
HARUNA, Masao et al. (Kantetsu Tsukuba Bldg. 6F, 1-1-1 Oroshi-machi, Tsuchiura-sh, Ibaraki 47, 〒3000847, JP)
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