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Title:
MONOFLUOROPHOSPHATE ESTER SALT, METHOD FOR PRODUCING SAME, AND FLUORINE ION-RELEASING COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2017/111087
Kind Code:
A1
Abstract:
[Problem] To provide: a monofluorophosphate ester salt capable of the sustained release of fluorine ions at a significant amount of release; a method for producing the monofluorophosphate ester salt; and a fluorine ion-releasing composition. [Solution] The monofluorophosphate ester salt of the present invention is characterized by being represented by chemical formula (1). (Mn+ represents any one species selected from the group consisting of a hydrogen ion, alkali metal ion, alkaline-earth metal ion, transition metal ion, rare-earth element ion, zinc ion, aluminum ion, gallium ion, indium ion, germanium ion, tin ion, lead ion, and onium ion. R1 represents a hydrocarbon group that has 1 to 20 carbons or a hydrocarbon group that has 1 to 20 carbons and that has at least one of any of a halogen atom, a heteroatom, and an unsaturated bond. n represents the valence.)

Inventors:
SAKAGUCHI TOSHITAKA (JP)
KATSURA YOSHIFUMI (JP)
YAMAMOTO MASASHI (JP)
NISHIDA TETSUO (JP)
Application Number:
PCT/JP2016/088497
Publication Date:
June 29, 2017
Filing Date:
December 22, 2016
Export Citation:
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Assignee:
STELLA CHEMIFA CORP (JP)
International Classes:
C07F9/14; A61K8/69; A61K31/661; A61K33/16; A61P1/02; A61Q11/00
Domestic Patent References:
WO2016024496A12016-02-18
Foreign References:
US3997504A1976-12-14
JP2008231026A2008-10-02
JP2013521337A2013-06-10
Other References:
STOELZER, C. ET AL.: "Infrared spectroscopic studies on fluorophosphorous compounds. II. Fluorophosphorous compound salts. The stretching vibration in the POO system and the structure of fluorothiophosphates on the bases of their infrared spectrum", ZEITSCHRIFT FUER ANORGANISCHE UND ALLGEMEINE CHEMIE, vol. 339, no. 1-2, 1965, pages 38 - 43, ISSN: 0044-2313
LIPKIN, DAVID ET AL.: "The Action of hydrogen fluoride on nucleotides and other esters of phosphorus(V) acids", JOURNAL OF ORGANIC CHEMISTRY, vol. 34, no. 6, 1969, pages 1539 - 1547, XP055396810, ISSN: 0022-3263
REDDY, GADE S. ET AL.: "31P and 19F nuclear magnetic resonance studies of phosphorus- fluorine compounds, Zeitschrift fuer Naturforschung", TEIL B: ANORGANISCHE CHEMIE, ORGANISCHE CHEMIE, BIOCHEMIE, BIOPHYSIK, BIOLOGIE, vol. 25, no. 11, 1970, pages 1199 - 1214, ISSN: 0044-3174
Attorney, Agent or Firm:
KOYAMA Yasushi (JP)
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