Title:
MONOOXYGENASE AND APPLICATION THEREOF IN PREPARING OPTICALLY PURE SULFOXIDE
Document Type and Number:
WIPO Patent Application WO/2020/108462
Kind Code:
A1
Abstract:
Provided is a monooxygenase of which the acid sequence is obtained by mutation of an amino acid sequence shown in SEQ ID NO: 2. The monooxygenase may be used for preparing chiral sulfoxide drugs and used for producing proton pump inhibitors of drugs for treating gastric ulcers.
Inventors:
ZHANG YAN (CN)
YU HUILEI (CN)
XU JIANHE (CN)
WU YINQI (CN)
ZHAO QIAN (CN)
YU HUILEI (CN)
XU JIANHE (CN)
WU YINQI (CN)
ZHAO QIAN (CN)
Application Number:
PCT/CN2019/120798
Publication Date:
June 04, 2020
Filing Date:
November 26, 2019
Export Citation:
Assignee:
UNIV EAST CHINA SCIENCE & TECH (CN)
JIANGSU AOSAIKANG PHARM CO LTD (CN)
JIANGSU AOSAIKANG PHARM CO LTD (CN)
International Classes:
C07K14/00; C12N1/21; C12N9/02; C12N15/53; C12P11/00; C12P17/16; C12R1/01
Foreign References:
| CN102884178A | 2013-01-16 | |||
| CN108118035A | 2018-06-05 | |||
| CN101372676A | 2009-02-25 |
Other References:
DATABASE GenBank 12 January 2018 (2018-01-12), Database accession no. WP_045432192
Attorney, Agent or Firm:
BEIJING EAST LINDEN IP CO., LTD. (CN)
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