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Title:
Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and the uses thereof
Document Type and Number:
WIPO Patent Application WO1992004359
Kind Code:
A3
Inventors:
ARORA SUNDERSHAN K (US)
WHISTLER ROY L (US)
THOMAS ALBERT V (US)
Application Number:
US9106458W
Publication Date:
December 10, 1992
Filing Date:
September 12, 1991
Export Citation:
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Assignee:
GREENWICH PHARMACEUTICALS, INC.
International Classes:
A61K31/70; A61K31/7028; A61P29/00; A61P37/00; C07H9/04; C07H13/04; C07H15/04; C07H15/10; C07H15/12; C07H15/14; C07H15/18; C07H15/26; C07H19/01; (IPC1-7): C07H15/04; C07H15/12; C07H15/14; C07H15/26; C07H19/01; A61K31/70
Foreign References:
FR2457300A11980-12-19
FR2370753A11978-06-09
US4735934A1988-04-05
EP0379397A21990-07-25
EP0404136A21990-12-27
Other References:
Chemical Abstracts, vol. 99, no. 3, 18 July 1983, (Columbus, Ohio, US), A. YAGI et al.: "Studies on the constituents of Zizyphi fructus. IV. Isolation of an antiallergic component, ethyl alpha-D-fructofuranoside from ethanol extract of Zizyphi fructus", see page 28, abstract no. 16149k, & YAKUGAKU ZASSHI 1981, 101(8), 700-7, see abstract
J. Med. Chem., vol. 25, 1982, American Chemical Society, Y. HARAGUCHI et al.: "A specific inhibitor of IgE-antibody formation: n-pentyl beta-D-fructopyranoside", pages 1495-1499, see page 1495, paragraph 1; page 1496, tables I,II, compounds 1,2,13
J. Chem. Soc., Perkin I, 1981, R. CORTES-GARCIA et al.: "Acetalatin of sucrose by acetal exchange with concomitant fissin of the glycosidic bond. Some new acetals of D-glucose and methyl alpha-D fructofuranoside", pages 3176-3181, see page 3180, column 2, lines 24-32, compound 7
J. Med. Chem., vol. 32, 1989, American Chemical Society, A.B. REITZ et al.: "Carbohydrate biguanides as potential hypoglycemic agents", pages 2110-2116, see page 2113, column 2, lines 30-54
Collection Czechoslov. Chem. Commun., vol. 34, 1969, J. JARY et al.: "Amino sugars. XX. Synthesis of 3-amino- and 6-amino-deoxyhexoses, of the gluco and allo configuration", pages 1452-1458, see page 1455, compound Va; page 1457, compound XVa
Chemical Abstracts, vol. 78, no. 25, 25 June 1973, (Columbus, Ohio, US), R. NEUMANN et al.: "Browning reactions of N-substituted 6-aminoaldoses. 1.", see page 453, abstract no. 160029e, & Z. CHEM. 1973, vol. 13, no. 2, pages 58-59, see abstract
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