Title:
MONOSULFONIC PHENYLTETRAZOLE COMPOUNDS WITH APPLICATIONS
Document Type and Number:
WIPO Patent Application WO/2017/080443
Kind Code:
A1
Abstract:
A class of compounds of monosulfonic phenyltetrazole, with the structure of 2- (R1 phenyl) -5 (2-sulfonic phenyl) -2H-tetrazole. The 2-sulfonic phenyl tetrazolium salt of this invention has advantages of low toxicity, short synthetic route, easy control of purity and quality. As the 2-sulfonic phenyl tetrazolium salts has almost no absorption at 450 nm where the reduzate has greater absorption, spectrophotometry can simply and rapidly determine the activity of glutamate dehydrogenase, or the content of NADH/NADPH.
Inventors:
RUAN BENFANG HELEN (US)
RUAN JENNIFER JIN (US)
RUAN JENNIFER JIN (US)
Application Number:
PCT/CN2016/105133
Publication Date:
May 18, 2017
Filing Date:
November 09, 2016
Export Citation:
Assignee:
HANGZHOU JENNIFER BIOTECH CO LTD (CN)
International Classes:
C07D257/04; C07D401/04; C07D403/04; C07D405/04; C07D409/04; C07D413/04; C07D417/04; C12Q1/32; C12Q1/34; G01N21/31
Domestic Patent References:
| WO2004063353A2 | 2004-07-29 | |||
| WO2004063353A2 | 2004-07-29 |
Foreign References:
| JP2007289096A | 2007-11-08 | |||
| US20070111274A1 | 2007-05-17 | |||
| JPS5524103A | 1980-02-21 | |||
| JPS5661367A | 1981-05-26 | |||
| US6063587A | 2000-05-16 | |||
| CN105418526A | 2016-03-23 | |||
| US20070111274A1 | 2007-05-17 | |||
| JPS5524103B2 | 1980-06-26 | |||
| JPS5661367A | 1981-05-26 | |||
| US6063587A | 2000-05-16 |
Other References:
See also references of EP 3380457A4
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