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Title:
A MOTION-COMPENSATED CONFOCAL MICROSCOPE
Document Type and Number:
WIPO Patent Application WO/2012/151546
Kind Code:
A3
Abstract:
A motion-compensated confocal microscope includes a laser scanning system, a fiber-optic component having a proximal end and a distal end such that the fiber-optic component is optically coupled to the laser scanning system to receive illumination light at the proximal end and to emit at least a portion of the illumination light at the distal end, and a detection system configured to receive and detect light returned from a specimen being observed and to output an image signal. The light returned from the specimen is received by the distal end of the fiber-optic component and transmitted back and out the proximal end of the fiber-optic component. The motion-compensated confocal microscope also includes a motion compensation system connected to at least one of the distal end of the fiber-optic component or to the specimen to move at least one of the distal end of the fiber-optic component or the specimen to compensate for relative motion between the distal end of the fiber-optic component and a portion of the specimen being observed.

Inventors:
KANG JIN U (US)
HUANG YONG (US)
ZHANG KANG (US)
Application Number:
PCT/US2012/036643
Publication Date:
January 31, 2013
Filing Date:
May 04, 2012
Export Citation:
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Assignee:
UNIV JOHNS HOPKINS (US)
KANG JIN U (US)
HUANG YONG (US)
ZHANG KANG (US)
International Classes:
G02B21/00; G01B9/04
Foreign References:
US20020163715A12002-11-07
US20080278781A12008-11-13
US20010024320A12001-09-27
Other References:
HUANG, Y. ET AL.: "A motion compensated fiber optic confocal microscope based on common-path optical coherent tomography distance sensor", PROC. SPIE 7894 , OPTICAL FIBERS, SENSORS, AND DEVICES FOR BIOMEDICAL DIAGNOSTICS AND TREAT- MENT, vol. XI, 16 February 2011 (2011-02-16), pages 789408
Attorney, Agent or Firm:
DALEY, Henry J. (P.O. Box 34385Washington, District of Columbia, US)
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