Title:
MOTOR CONTROL FUNCTION IMPROVING AGENT
Document Type and Number:
WIPO Patent Application WO/2018/124011
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a motor control function improving agent that improves motor control functions which have deteriorated due to aging or fatigue, and a method for evaluating or selecting the motor control function improving agent. Specifically provided is a motor control function improving agent that comprises a GIP function inhibitor as an active component.
Inventors:
OKAHARA FUMIAKI (JP)
KOGA YOSHITAKA (JP)
MORI TAKUYA (JP)
KOGA YOSHITAKA (JP)
MORI TAKUYA (JP)
Application Number:
PCT/JP2017/046526
Publication Date:
July 05, 2018
Filing Date:
December 26, 2017
Export Citation:
Assignee:
KAO CORP (JP)
International Classes:
A61K45/00; A61K31/16; A61K31/4045; A61K39/395; A61P19/00; A61P21/00; A61P25/00; G01N33/15; G01N33/50
Domestic Patent References:
| WO2016104439A1 | 2016-06-30 | |||
| WO2003097031A1 | 2003-11-27 | |||
| WO2016104439A1 | 2016-06-30 | |||
| WO2003097031A1 | 2003-11-27 | |||
| WO2001087341A1 | 2001-11-22 | |||
| WO2012121302A1 | 2012-09-13 |
Foreign References:
| JP2013138638A | 2013-07-18 | |||
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Other References:
THANGTHAENG N. ET AL.: "Daily supplementation with mushroom(Agaricus bisporus) improves balance and working memory in aged rats", NUTR RES., vol. 35, no. 12, December 2015 (2015-12-01), pages 1079 - 1084, XP029338471, ISSN: 0271-0166, Retrieved from the Internet DOI: 10.1016/j.nutres.2015.09.012
KALYANI RR. ET AL.: "Diabetes and altered glucose metabolism with aging", ENDCRINOL METAB CLIN NORTH AM., vol. 42, no. 2, June 2013 (2013-06-01), pages 333 - 347, XP055508492, ISSN: 0889-8529, DOI: 10.1016/j.ecl.2013.02.010
WEISS EP . ET AL.: "Calorie restriction and matched weight loss from exercise : Independent and additive effects on glucoregulation and the incretin system in overweight women and men", DIABETES CARE, vol. 38, no. 7, July 2015 (2015-07-01), pages 1253 - 1262, XP055508512, ISSN: 0149-5992, DOI: 10.2337/dc14-2913
SHUFEN HAN ET AL.: "Dietary fiber prevents obesity-related liver lipotoxicity by modulating sterol-regulatory element binding protein pathway in C57BL/6J mice fed a high-fat/cholesterol diet", SCIENTIFIC REP., vol. 5, 29 October 2015 (2015-10-29), XP055508523, ISSN: 2045-2322, DOI: 10.1038/srep15256
KELLY KR . ET AL.: "The glucose-dependent insulinotropic polypeptide and glucose-stimulated insulin response to exercise training and diet in obesity", AM J PHYSIOL ENDOCRINOL METAB., vol. 296, no. 6, 1 June 2009 (2009-06-01), pages E1269 - E1274, XP055508527, ISSN: 0193-1849, DOI: 10.1152/ajpendo.00112.2009
HARUO SUGI ET AL.: "Zintai Kinou Seirigaku (Physiology of Human Body Functions), 5th revision", 2010, NANZANDO
TAKASHI MATSUNAGA: "Memai ni taisuru Yakubutsu Ryoho no Sentaku to Koka (Selection and effect of drug therapy on dizziness", vol. 65, 1972, JIBI RINSHO, pages: 653 - 671
YASUSHI UCHIYAMAKOJI TOKUMASU: "Zenteimeiro-sei Sikkan ni tomonau Memai/Heiko shogai Kanja no Undo Ryoho (Exercise therapy of dizziness and dysequilibrium patients due to vestibular labyrinthine disease", EQUILIBRIUM RESEARCH, vol. 50, no. 2, 1991, pages 199 - 205
MIYAWAKI K ET AL., NAT. MED., vol. 8, no. 7, 2002, pages 738 - 42
SCIENCE, vol. 227, 1985, pages 1435
MACCFFERTY, J. ET AL., NATURE, vol. 348, 1990, pages 552 - 554
TIM CLACKSON ET AL., NATURE, vol. 352, 1991, pages 642 - 628
KOHLER ET AL., NATURE, vol. 256, 1975, pages 495 - 497
See also references of EP 3560515A4
KALYANI RR. ET AL.: "Diabetes and altered glucose metabolism with aging", ENDCRINOL METAB CLIN NORTH AM., vol. 42, no. 2, June 2013 (2013-06-01), pages 333 - 347, XP055508492, ISSN: 0889-8529, DOI: 10.1016/j.ecl.2013.02.010
WEISS EP . ET AL.: "Calorie restriction and matched weight loss from exercise : Independent and additive effects on glucoregulation and the incretin system in overweight women and men", DIABETES CARE, vol. 38, no. 7, July 2015 (2015-07-01), pages 1253 - 1262, XP055508512, ISSN: 0149-5992, DOI: 10.2337/dc14-2913
SHUFEN HAN ET AL.: "Dietary fiber prevents obesity-related liver lipotoxicity by modulating sterol-regulatory element binding protein pathway in C57BL/6J mice fed a high-fat/cholesterol diet", SCIENTIFIC REP., vol. 5, 29 October 2015 (2015-10-29), XP055508523, ISSN: 2045-2322, DOI: 10.1038/srep15256
KELLY KR . ET AL.: "The glucose-dependent insulinotropic polypeptide and glucose-stimulated insulin response to exercise training and diet in obesity", AM J PHYSIOL ENDOCRINOL METAB., vol. 296, no. 6, 1 June 2009 (2009-06-01), pages E1269 - E1274, XP055508527, ISSN: 0193-1849, DOI: 10.1152/ajpendo.00112.2009
HARUO SUGI ET AL.: "Zintai Kinou Seirigaku (Physiology of Human Body Functions), 5th revision", 2010, NANZANDO
TAKASHI MATSUNAGA: "Memai ni taisuru Yakubutsu Ryoho no Sentaku to Koka (Selection and effect of drug therapy on dizziness", vol. 65, 1972, JIBI RINSHO, pages: 653 - 671
YASUSHI UCHIYAMAKOJI TOKUMASU: "Zenteimeiro-sei Sikkan ni tomonau Memai/Heiko shogai Kanja no Undo Ryoho (Exercise therapy of dizziness and dysequilibrium patients due to vestibular labyrinthine disease", EQUILIBRIUM RESEARCH, vol. 50, no. 2, 1991, pages 199 - 205
MIYAWAKI K ET AL., NAT. MED., vol. 8, no. 7, 2002, pages 738 - 42
SCIENCE, vol. 227, 1985, pages 1435
MACCFFERTY, J. ET AL., NATURE, vol. 348, 1990, pages 552 - 554
TIM CLACKSON ET AL., NATURE, vol. 352, 1991, pages 642 - 628
KOHLER ET AL., NATURE, vol. 256, 1975, pages 495 - 497
See also references of EP 3560515A4
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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