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Title:
MOUSE ARTIFICIAL CHROMOSOME VECTOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/177163
Kind Code:
A1
Abstract:
This application provides: a novel mouse artificial chromosome vector that is stable in rodent cells or tissues or rodent individuals, specifically a mouse artificial chromosome vector derived from a mouse chromosome selected from the group consisting of mouse chromosome 10 and mouse chromosome 16; a cell or non-human animal containing this vector; and the use of the vector for protein production and human antibody manufacture.

Inventors:
KAZUKI Yasuhiro (86 Nishi-cho, Yonago-sh, Tottori 03, 〒6838503, JP)
OSHIMURA Mitsuo (86 Nishi-cho, Yonago-shi Tottori, 03, 〒6838503, JP)
ABE Satoshi (86 Nishi-cho, Yonago-shi Tottori, 03, 〒6838503, JP)
Application Number:
JP2019/010953
Publication Date:
September 19, 2019
Filing Date:
March 15, 2019
Export Citation:
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Assignee:
NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (4-101, Koyamacho-Minami Tottori-sh, Tottori 50, 〒6808550, JP)
TRANS CHROMOSOMICS, INC. (86 Nishi-cho, Yonago-shi Tottori, 03, 〒6838503, JP)
International Classes:
C12N15/85; A01K67/027; C12N5/10; C12N15/12; C12N15/13; C12N15/16; C12P21/02; C12P21/08; A61K31/711; A61K38/18; A61K38/19; A61K38/22; A61K38/36; A61K38/43; A61K48/00; A61P5/00; A61P7/00; A61P7/04; A61P21/04; A61P25/28; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07K16/18
Domestic Patent References:
WO2011083870A12011-07-14
WO2008013067A12008-01-31
Foreign References:
JP2015119643A2015-07-02
Other References:
TAKIGUCHI M. ET AL.: "A Novel and Stable Mouse Artificial Chromosome Vector", ACS SYNTHETIC BIOLOGY, vol. 3, 9 October 2012 (2012-10-09), pages 903 - 914, XP055472980, doi:10.1021/sb3000723
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (Atago Green Hills MORI Tower 32F, 5-1 Atago 2-chome, Minato-k, Tokyo 32, 〒1056232, JP)
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