Title:
MPG ADDED TO FERMENTATION
Document Type and Number:
WIPO Patent Application WO2004003187
Kind Code:
A3
Abstract:
A method for fermenting a microorganism, producing a polypeptide of interest, in a culture medium of at least 50 litres, comprising:adding one or more compounds selected from the group consisting of monopropylene glycol, ethylene glycol, trehalose, xylitol, arabitol, dulcitol, mannitol, erythritol, cellobiose and sorbitol, to the culture medium before and/or during fermentation, wherein the compound is low metabolizable.
Inventors:
KAASGAARD SVEND (DK)
BANKE NIELS (DK)
HANSEN KIM UHRE (DK)
BANKE NIELS (DK)
HANSEN KIM UHRE (DK)
Application Number:
PCT/DK2003/000455
Publication Date:
March 18, 2004
Filing Date:
July 01, 2003
Export Citation:
Assignee:
NOVOZYMES AS (DK)
KAASGAARD SVEND (DK)
BANKE NIELS (DK)
HANSEN KIM UHRE (DK)
KAASGAARD SVEND (DK)
BANKE NIELS (DK)
HANSEN KIM UHRE (DK)
International Classes:
C12N1/38; C12N9/00; C12N9/28; (IPC1-7): C12N9/00; C12N1/38
Domestic Patent References:
| WO2003014339A2 | 2003-02-20 |
Foreign References:
| CH667673A5 | 1988-10-31 | |||
| DD153495A3 | 1982-01-13 | |||
| US5260202A | 1993-11-09 | |||
| GB1001173A | 1965-08-11 | |||
| US4673647A | 1987-06-16 | |||
| US4016039A | 1977-04-05 |
Other References:
PATENT ABSTRACTS OF JAPAN vol. 009, no. 153 (C - 288) 27 June 1985 (1985-06-27)
ESTEVE-ROMERO JOSEP S ET AL: "Purification of thermamylase in multicompartment electrolyzers with isoelectric membranes: The problem of protein solubility.", ELECTROPHORESIS, vol. 17, no. 7, 1996, pages 1242 - 1247, XP001104576, ISSN: 0173-0835
ESTEVE-ROMERO JOSEP S ET AL: "Purification of thermamylase in multicompartment electrolyzers with isoelectric membranes: The problem of protein solubility.", ELECTROPHORESIS, vol. 17, no. 7, 1996, pages 1242 - 1247, XP001104576, ISSN: 0173-0835
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