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Patent Searching and Data


Title:
MRP3 GENES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO2004075842
Kind Code:
A3
Abstract:
A nucleic acid capable of driving the expression of a reporter gene in a cancer cell line is disclosed. A polypeptide able to confer multidrug-resistance on a cell is disclosed. Also disclosed are nucleic acids encoding the polypeptide, expression vectors, transformant host cell lines expressing the polypeptide, and antibodies binding to the polypeptide. Screening, diagnostic and treatment methods using the above polypeptide, nucleic acids, antibodies and host cell lines are also within the scope of this invention.

Inventors:
CHEN LAN BO (US)
AUCLAIR DANIEL (US)
Application Number:
US2004005335W
Publication Date:
November 10, 2005
Filing Date:
February 24, 2004
Export Citation:
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Assignee:
DANA-FARBER CANCER INSTITUTE, INC.
CHEN, LAN BO
AUCLAIR, DANIEL
International Classes:
C07H21/04; C07K14/705; C07K16/30; C12N15/12; G01N33/574; A61K38/00; A61K; (IPC1-7): C07K13/00; C07H21/04
Other References:
DUSSAULT ET AL: 'Peptide Mimetic HIV Protease Inhibitors Are ligands for the Orphan Receptor SXR.' THE JOURNAL OF BIOLOGICAL CHEMISTRY vol. 276, no. 36, 07 September 2001, pages 33309 - 33312, XP001029156
HAU P. ET AL: 'Pegylated Liposomal Doxorubicin-Efficacy in Patiens with Recurrent High-Grade Glioma.' CANCER vol. 100, no. 6, 2004, pages 1199 - 1207, XP002989617
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