Title:
MUCIN 5AC SPECIFIC HUMAN ANTIBODY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2013/157105
Kind Code:
A1
Abstract:
The present invention pertains to: a mucin 5AC specific human antibody in which the framework region has specific sequential characteristics; an antigen-binding fragment of the mucin 5AC specific human antibody; and a pharmaceutical composition for the treatment of diseases involving the abnormal expression of mucin 5AC, said pharmaceutical composition containing the mucin 5AC specific human antibody and/or the antigen-binding fragment.
Inventors:
HOSHI HIROTAKA
KIKUCHI MAMI
AOKI RIEKO
UCHIDA MOTOYUKI
SAWADA TETSUJI
NAKANISHI TAKESHI
HIRAKAWA KOSEI
KITAMURA MASAYA
KIKUCHI MAMI
AOKI RIEKO
UCHIDA MOTOYUKI
SAWADA TETSUJI
NAKANISHI TAKESHI
HIRAKAWA KOSEI
KITAMURA MASAYA
Application Number:
PCT/JP2012/060508
Publication Date:
October 24, 2013
Filing Date:
April 18, 2012
Export Citation:
Assignee:
UNIV OSAKA CITY (JP)
HOSHI HIROTAKA
KIKUCHI MAMI
AOKI RIEKO
UCHIDA MOTOYUKI
SAWADA TETSUJI
NAKANISHI TAKESHI
HIRAKAWA KOSEI
KITAMURA MASAYA
HOSHI HIROTAKA
KIKUCHI MAMI
AOKI RIEKO
UCHIDA MOTOYUKI
SAWADA TETSUJI
NAKANISHI TAKESHI
HIRAKAWA KOSEI
KITAMURA MASAYA
International Classes:
C07K16/18; A61K39/395; A61P35/00; C07K16/46; C12N15/09; C12P21/08
Foreign References:
| JP2011042581A | 2011-03-03 | |||
| JP2010077133A | 2010-04-08 | |||
| JP2007515925A | 2007-06-21 | |||
| JPH07203974A | 1995-08-08 |
Other References:
TETSUJI SAWADA ET AL.: "Mucin Hyoteki to shita Suigan no Kotai Ryoho", JAPANESE JOURNAL OF CLINICAL MEDICINE, vol. 64, no. ISS.1, 2006, pages 274 - 278
TAMAMORI Y. ET AL.: "Granulocyte-colony stimulating factor enhances chimeric antibody Nd2 dependent cytotoxicity against pancreatic cancer mediated by polymorphonuclear neutrophils", INTERNATIONAL JOURNAL OF ONCOLOGY, vol. 21, 2002, pages 649 - 654
TAMAMORI Y. ET AL.: "Granulocyte-colony stimulating factor enhances chimeric antibody Nd2 dependent cytotoxicity against pancreatic cancer mediated by polymorphonuclear neutrophils", INTERNATIONAL JOURNAL OF ONCOLOGY, vol. 21, 2002, pages 649 - 654
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (JP)
Patent business corporation Hara [Kenzo] international patent firm (JP)
Patent business corporation Hara [Kenzo] international patent firm (JP)
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