A MULTI-INDEX DETECTION MICROFLUIDIC CHIP AND METHODS OF USE

Title:

A MULTI-INDEX DETECTION MICROFLUIDIC CHIP AND METHODS OF USE

Document Type and Number:

WIPO Patent Application WO/2015/131662

Kind Code:

A1

Abstract:

A multi-index detection microfluidic chip is provided. A bottom plate (1) and a cover plate (2) that matches the bottom plate (1) and seals it are provided in the microfluidic chip. The center of the microfluidic chip has a through-hole (3). The bottom plate (1) has one or more wave-shaped main channel (s ) (4), one end of each of the main channel (4) connected to a sample injection hole (9) on the bottom plate (1), and the other end connected to an exhaust hole (10) on the bottom plate (1). The valley on the main channel (1) is distal to the through-hole (3), and the peak is proximal to the through-hole (3). Each valley of the main channel (1) is connected to a reaction chamber (6) by a linking channel (5). The linking channel (5) comprises one or more buffering chambers (7). The microfluidic chip can be used in detection by fluorescence, turbidity, color, detection equipment, and/or direct observation by the naked eyes. The detection is real-time as the reaction occurs or after the reaction.

Inventors:

WANG LEI (CN)
ZHANG GUOHAO (CN)
ZHOU XINYING (CN)
XIN JUAN (CN)
ZHANG YAO (CN)
LIN MINGXIAN (CN)
HUANG GUOLIANG (CN)
WANG CAN (CN)
XING WANLI (CN)
CHENG JING (CN)

Application Number:

PCT/CN2015/000141

Publication Date:

September 11, 2015

Filing Date:

March 06, 2015

Export Citation:

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Assignee:

CAPITALBIO CORP (CN)
UNIV TSINGHUA (CN)

International Classes:

B01L3/00

Domestic Patent References:

WO2013077391A1

2013-05-30

Foreign References:

CN103831140A	2014-06-04
CN102369443A	2012-03-07
EP2028496A2	2009-02-25
US20020142481A1	2002-10-03

Other References: