Title:
MULTI-LAYERED POLYMER BASED MOISTURE BARRIER STRUCTURE FOR MEDICAL GRADE PRODUCTS
Document Type and Number:
WIPO Patent Application WO2001056783
Kind Code:
A8
Abstract:
The present invention provides a multiple layer thermoplastic structure of a (1) skin layer selected from the group consisting of polypropylene, ethylene homopolymers having a density of from about 0.930 g/cc to about 0.960 g/cc, and ethylene homopolymers having a density of from about 0.930 g/cc to about 0.960 c/cc blended with an ethylene and alpha -olefin copolymers having a density less than about 0.930 g/cc, the skin layer having a thickness of greater than about 3.0 mils; (2) a radio frequency susceptible layer adhered to the skin layer, the radio frequency susceptible layer having a dielectric loss greater than 0.05 at 1-60 MHz and at temperatures of ambient to 250 DEG C, the radio frequency susceptible layer having: (a) a first polyolefin selected from the group consisting of polypropylene and polypropylene copolymers, (b) a second polyolefin selected from the group consisting of ethylene copolymers, ultra-low density polyethylene, polybutene, and butene ethylene copolymers; (c) a radio frequency susceptible polymer selected from the group consisting of (i) ethylene copolymers having 50-85 % ethylene content with comonomers selected from a first group consisting of acrylic acid, methacrylic acid, ester derivatives of acrylic acid with alcohols having 1-10 carbons, ester derivatives of methacrylic acid with alcohols having 1-10 carbons, vinyl acetate, and vinyl alcohol (ii) homopolymers and copolymers containing at least one segment of urethanes, esters, ureas, imides, sulfones, and amides, and (d) a compatibilizing agent of a styrene and hydrocarbon copolymer; wherein the structure when fabricated into a 50 ml container has a water vapor transmission rate of less than 8 % by weight after the container has been autoclaved at 121 DEG C for 20 minutes and stored for 90 days in an environmentally regulated compartment having 15 % relative humidity at 40 DEG C.
Inventors:
LING MICHAEL T K
WOO LECON
WOJNAROWSKI ROBERT
SHAH KETAN
NEBGEN GREGG
DING YUAN-PANG SAMUEL
KALYANKAR VARSHA
ANDERSON KEITH M K
ZAKARIJA LILLIAN G
CRAMER COLLEEN S
SCHARF MICHAEL
ROSENBAUM LARRY A
WOO LECON
WOJNAROWSKI ROBERT
SHAH KETAN
NEBGEN GREGG
DING YUAN-PANG SAMUEL
KALYANKAR VARSHA
ANDERSON KEITH M K
ZAKARIJA LILLIAN G
CRAMER COLLEEN S
SCHARF MICHAEL
ROSENBAUM LARRY A
Application Number:
PCT/US2001/003993
Publication Date:
November 21, 2002
Filing Date:
February 07, 2001
Export Citation:
Assignee:
BAXTER INT (US)
International Classes:
A61L31/00; B32B7/025; B32B27/08; B32B27/32; C08L23/08; C08L23/10; C08L25/04; C08L53/00; C08L53/02; (IPC1-7): B32B27/08; B32B27/32
Download PDF: