MULTI-POLYMER-COATED MAGNETIC NANOCLUSTERS - MASSACHUSETTS INST TECHNOLOGY

Title:

MULTI-POLYMER-COATED MAGNETIC NANOCLUSTERS

Document Type and Number:

WIPO Patent Application WO2005076938

Kind Code:

A3

Abstract:

The present invention relates to multi-polymer-coated magnetic nanoclusters, aqueous magnetic fluids comprising same, and methods of their use in separation procedures. The multi-polymer-coated magnetic nanoclusters comprise a super paramagnetic core, with a first polymer attached Thereto, which does not render the first polymer-super paramagnetic particle complex colloidally stake, and a second polymer attached thereto, which stabilizes the complex of minti-polymer-coated B0gnetïA nanoparticles. Methods of use comprise methods of separation, including separation of expressed protein from cells and viruses expressing the same.

Inventors:

HATTON T ALAN (US)
WANG DANIEL I C (US)
LAIBINIS PAUL (US)
DITSCH ANDRE (US)

Application Number:

PCT/US2005/003666

Publication Date:

June 08, 2006

Filing Date:

February 09, 2005

Export Citation:

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Assignee:

MASSACHUSETTS INST TECHNOLOGY (US)
HATTON T ALAN (US)
WANG DANIEL I C (US)
LAIBINIS PAUL (US)
DITSCH ANDRE (US)

International Classes:

G01N33/543; C07K1/30; C08K3/18; C08K9/08; C08K9/12; G01N33/53; G01N33/534; G01N33/553; G01N33/567

Foreign References:

US6133047A

2000-10-17

Other References: