Title:
MULTIFUNCTIONAL LIGAND FOR USE AS A DIAGNOSTIC OR THERAPEUTIC PHARMACEUTICAL
Document Type and Number:
WIPO Patent Application WO1992019573
Kind Code:
A3
Abstract:
A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises either a phosphorous or germanium core and at least two hydrazine groups forming a ligand for bonding to a metal extending from the phosphorous or germanium core.
Inventors:
KATTI KATTESH V (US)
VOLKERT WYNN ARTHUR (US)
KETRING ALAN REED (US)
VOLKERT WYNN ARTHUR (US)
KETRING ALAN REED (US)
Application Number:
PCT/US1992/003662
Publication Date:
January 07, 1993
Filing Date:
May 01, 1992
Export Citation:
Assignee:
UNIV MISSOURI (US)
International Classes:
A61K51/04; C07F7/00; C07F7/30; C07F9/06; C07F9/22; C07F9/44; C07F9/535; C07F13/00; C07F15/00; C07F15/06; C07F19/00; (IPC1-7): C07C/
Other References:
Tetrahechon, Vol. 32, 1976, MAJORAL et al., "Keterocycler Content Du Phosphore XXXIX", pp. 2633-2644
CHEMICAL ABSTRACTS, Volume 87, No. 19, issued 7 November 1977 (Columbus, Ohio, USA), GRAPOV et al., "Some reactions of phosphours, his acid dihydrazides", Abstract No. 152323s; & Zh obshch Khim (1977), 47(8), pp. 1704-11.
CHEMICAL ABSTRACTS, Volume 88, No. 7, issued 13 February 1978 (Columbus, Ohio, USA), MAJORAL et al., "Heterocycles containing phosphous XXXII", Abstract No. 50967h; & Heterocyclic Chemistry (1977), 14(5), pp. 749-55.
CHEMICAL ABSTRACTS, Volume 76, No. 20, issued 15 May 1972, HUANG et al., "Polymers containing phosphous", Abstract No. 113579h; & Kozyo Kogaher Zasshi (1971), 77(11), pp. 2406-9.
Chemische Berichte, Vol. 100, No. 7 (1967), HORN et al., "Darstellung von Thiophosphoyltrihydrazide, ect.", pp. 2258-2260
CHEMICAL ABSTRACTS, Volume 69, No. 25, issued 16 December 1968, SCOLER et al., "N,N'-Disubstituted P-phenylphosphonothioic diamcles", Abstract No. 106808; & J. Chem. Eng. Data (1968), 13(4), pp. 571-2.
CHEMICAL ABSTRACTS, Volume 87, No. 19, issued 7 November 1977 (Columbus, Ohio, USA), GRAPOV et al., "Some reactions of phosphours, his acid dihydrazides", Abstract No. 152323s; & Zh obshch Khim (1977), 47(8), pp. 1704-11.
CHEMICAL ABSTRACTS, Volume 88, No. 7, issued 13 February 1978 (Columbus, Ohio, USA), MAJORAL et al., "Heterocycles containing phosphous XXXII", Abstract No. 50967h; & Heterocyclic Chemistry (1977), 14(5), pp. 749-55.
CHEMICAL ABSTRACTS, Volume 76, No. 20, issued 15 May 1972, HUANG et al., "Polymers containing phosphous", Abstract No. 113579h; & Kozyo Kogaher Zasshi (1971), 77(11), pp. 2406-9.
Chemische Berichte, Vol. 100, No. 7 (1967), HORN et al., "Darstellung von Thiophosphoyltrihydrazide, ect.", pp. 2258-2260
CHEMICAL ABSTRACTS, Volume 69, No. 25, issued 16 December 1968, SCOLER et al., "N,N'-Disubstituted P-phenylphosphonothioic diamcles", Abstract No. 106808; & J. Chem. Eng. Data (1968), 13(4), pp. 571-2.
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